PMID: 6162486Jan 1, 1980Paper

Use of nuclear Overhauser effect in the study of peptides and proteins

Biochimie
B P RoquesD Marion

Abstract

The nuclear Overhauser effect (NOE) leads to changes in the intensity of signal(s) of a set of nuclei as a function of their respective distances. The use of NOE allows to obtain structural informations on peptides and proteins in solution as well as the study of interactions between small ligands and biomolecules. In this review, aspects of the basic theory of the NOE will be presented and the more recent applications of homonuclear and heteronuclear NOE's in biomolecules will be surveyed. Typical examples will be illustrated and limitations of the method will be discussed.

References

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Citations

Jul 1, 2008·Annual Review of Cell and Developmental Biology·Bharath S Mamathambika, James C Bardwell
Feb 21, 2002·Proceedings of the National Academy of Sciences of the United States of America·Murali C KrishnaJames B Mitchell
May 31, 1983·Biochemical and Biophysical Research Communications·M PtakC Brevard
Jul 1, 1987·International Journal of Peptide and Protein Research·P RoyB P Roques
Oct 1, 1989·International Journal of Peptide and Protein Research·A AumelasJ Martinez

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