PMID: 2110709Feb 1, 1990Paper

Use of Nutramin VLI Spofa for parenteral nutrition in the early post-injury period in polytrauma

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
F VyhnánekJ Kletenský

Abstract

The solution of branched-chain amino acids of gradually increasing concertration ranging from 22.7 to 43 per cent was administered to 15 patients with polytrauma as part of parenteral nutrition. Parenteral nutrition was started with during 24 hours after the trauma. The effect of parenteral nutrition was objectified by a twenty-four hour balance of water, ions, energy and nitrogen and by a follow-up of kinetics of amino acids in the plasma. It was found out that the increase of the share of branched-chain amino acids up to 43 per cent resulted in a pharmacodynamically efficient level of valine. There occurred gradual adjustment both of the levels of other aminoacids in the plasma and other metabolic changes including the restoration of proteosynthesis.

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