Use of Opioid Analgesics Before and After Gastric Bypass Surgery in Sweden: a Population-Based Study

Obesity Surgery
Stefan WallénIngmar Näslund

Abstract

Little is known regarding the use of opioid analgesics among patients who have undergone bariatric surgery. The Roux-en-Y gastric bypass (RYGB) procedure has been shown to significantly increase the rate of absorption of and exposure to morphine, raising concerns regarding the potentially increased risk of side-effects and the development of substance-use disorder. The aim of this study was to describe the pattern of opioid use over time following RYGB and to see if the pattern differs between patients with a high opioid consumption (HOC) prior to surgery and those with a low consumption (LOC). University Hospital of Örebro, Sweden. The study was a descriptive retrospective population-based cohort study where two registers with complete coverage were cross-matched. The study population comprised 35,612 persons (1628 HOC, and 33,984 LOC). After surgery, the number of HOC patients increased to 2218. Mean daily opioid consumption in the total population and the LOC group increased after surgery (p < .0005). In the HOC group, there was no difference between mean daily consumption before and after surgery. In this nationwide study, we have showed that there is an increase in consumption of opioid analgesics after gastric bypass surg...Continue Reading

References

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Citations

Nov 23, 2019·Scandinavian Journal of Pain·Amalie H SimoniAnne E Olesen
Jan 20, 2019·Obesity Surgery·Daniel Croxford, Mark C Kendall
Mar 22, 2021·The Surgical Clinics of North America·Afton M KoballRachel E Goetze
May 9, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Martin L Skogar, Magnus Sundbom
Aug 11, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Bjarni VidarssonMagnus Sundbom
Nov 5, 2021·Surgical Endoscopy·Jaewhan KimTed Adams

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