PMID: 11903401Mar 21, 2002Paper

Use of oral fluorescein angiography in the diagnosis of macular oedema within a diabetic retinopathy screening programme

Diabetic Medicine : a Journal of the British Diabetic Association
F M RazviR E Ryder

Abstract

To assess if oral fluorescein angiography (OFA) is a suitable screening method to detect macular oedema in diabetic retinopathy. Eighty-four diabetic patients were included in the study. They were from a consecutive series of patients attending the diabetic eye-screening clinic, with retinopathy at the macula requiring ophthalmology assessment. All patients were subsequently examined in the eye hospital, by ophthalmologist slit lamp biomicroscopy assessment as the gold standard, followed by oral fluorescein angiography. This study indicates a sensitivity of 92% and specificity of 81%. Only 4.8% of patients developed a minor reaction to oral fluorescein; 84.5% of images were of good quality. Oral fluorescein angiography is an efficient and highly sensitive tool for the detection of macular oedema. It can be used as an adjunct in the diabetic screening service to identify patients with oedema within a disc diameter of the macula. Ultimately it will ensure that only necessary and smaller numbers of patients are referred to ophthalmologists.

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Citations

May 8, 2002·Diabetes/metabolism Research and Reviews
Jun 1, 2006·Naunyn-Schmiedeberg's Archives of Pharmacology·Johannes PillNorbert Gretz

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