PMID: 32155120Mar 11, 2020Paper

Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressings Alone or Subsequent to Advanced Wound Therapies in Complex Wounds

Wounds : a Compendium of Clinical Research and Practice
Robert J Klein

Abstract

Chronic or senescent wounds are difficult to heal and often require a multimodal treatment plan. Negative pressure wound therapy (NPWT) or advanced wound dressings, such as oxidized regenerated cellulose (ORC)/collagen/silver-ORC dressings, can be used to promote granulation tissue development and stimulate wound healing in these complex wounds. This article examines the use of ORC/collagen/silver-ORC dressings alone or subsequent to advanced wound therapies in a retrospective cohort of 24 patients. Wounds were assessed upon presentation. If necessary, oral and/or intravenous antibiotics were administered. Each wound underwent sharp debridement. Patients received either ORC/collagen/silver-ORC dressings with a secondary dressing alone or following NPWT. Skin substitutes and epidermal grafting also were utilized to promote wound healing and wound size reduction. Twenty-four patients with an average age of 66.8 ± 12.7 years were treated. The most prevalent comorbidities were hypertension, diabetes, obesity, peripheral neuropathy, hyperlipidemia, coronary heart disease, and tobacco use. Wound types (N = 27) included diabetic foot ulcers, surgical wounds, traumatic wounds, an ulcer (secondary to chronic gout with tophi), and therma...Continue Reading

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