Use of propranolol in children with primary nocturnal enuresis

Sudanese Journal of Paediatrics
Hüseyin ÇaksenBülent Ataş

Abstract

In nocturnal enuresis, motivational therapy, alarm therapy, and drug therapy, such as anticholinergics, imipramine, and sertraline, are the mainstay of treatment. In the present study, we used motivational therapy, oxybutynin, and propranolol in children with primary nocturnal enuresis to determine if propranolol is an effective treatment. Fifty-two children with primary nocturnal enuresis were included in the study. Firstly, motivational therapy was given for 1 month to all patients. Patients who failed the motivational therapy were randomly given oxybutynin or propranolol. The patients were re-evaluated after 1 month of drug therapy. There was not a significant difference between oxybutynin and propranolol groups for initial frequency of nocturnal enuresis ( p > 0.05). Of 52 patients, 28 (53.8%) patients improved by motivational therapy. There were 14 patients in the oxybutynin group. One patient was excluded from the study because facial flushing and mouth drying developed in the first week of oxybutynin therapy. In oxybutynin group, 12 of 13 (92.3%) patients improved. There were 10 patients in the propranolol group. In the propranolol group, while nine (90%) patients did not improve, one patient had significant remission (9...Continue Reading

References

Dec 1, 1988·Postgraduate Medicine·S S Stoffer
Aug 1, 1983·Urology·S WalterJ K Kristensen
Dec 17, 2009·The Journal of Urology·Tryggve NeveusUNKNOWN International Children's Continence Society
Feb 27, 2010·Medical Hypotheses·M CarotenutoAntonio Pascotto
May 16, 2012·European Neurology·Jaime LinLuiz Celso Pereira Vilanova
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Aniruddh V DeshpandePremala Sureshkumar
Dec 25, 2012·Journal of Pediatric Urology·Israel FrancoUNKNOWN International Childrens's Continence Society
Sep 11, 2017·European Urology Focus·Bernhard Haid, Serdar Tekgül
Feb 26, 2019·Sudanese Journal of Paediatrics·Hüseyin ÇaksenBülent Ataş

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Citations

Mar 21, 2020·European Journal of Psychotraumatology·Sarah ThierréeWissam El-Hage
Feb 26, 2019·Sudanese Journal of Paediatrics·Hüseyin ÇaksenBülent Ataş

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