Use of rapid diagnostic tests for malaria in an emergency situation after the flood disaster in Mozambique

Public Health
M HashizumeS Wakai

Abstract

To determine how diagnosis of malaria may be improved by combining the use of rapid diagnostic tests (RDTs) for Plasmodium falciparum malaria with clinical diagnosis by the presence or history of fever compared with clinical diagnosis alone in emergency situations with flood-affected displaced populations in Mozambique. A cross-sectional study conducted at the emergency outpatient clinic in a village in the Chòkwè district of Gaza Province, 3 weeks after Cyclone Eline hit Mozambique in February 2000. A hundred and thirty children aged less than 15 years with clinical malaria were selected for examination by RDT and fluorescent microscopy using acridine orange as a reference test. The diagnosis of clinical malaria was made by a history of fever in the last three days or axillary temperature above 37.0 degrees C at the time of attending the emergency outpatient clinic. Two positive predictive values were calculated; RDTs combined with clinical diagnosis and clinical diagnosis alone. Positive predictive values of RDTs combined with clinical diagnosis by the presence of fever or history of fever were 87.6% (92/105) (95% confidence interval (CI) 80.8-92.8) compared with 74.6% (97/130) (95% CI 66.2-81.8) for clinical diagnosis alone....Continue Reading

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Citations

Jul 16, 2010·Journal of Environmental Management·Jinren NiAlistair G L Borthwick
Apr 21, 2009·Diagnostic Microbiology and Infectious Disease·Inge Versteeg, Petra F Mens
Feb 27, 2008·Tropical Medicine & International Health : TM & IH·Osama M E SeidahmedEldirdieri S Ahmed
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Sep 28, 2006·Nature Reviews. Microbiology·David BellJohn W Barnwell

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