PMID: 9431912Feb 12, 1998Paper

Use of ribotyping and hemolysin activity to identify highly virulent Streptococcus suis type 2 isolates

Journal of Clinical Microbiology
J StaatsM M Chengappa

Abstract

Nineteen Streptococcus suis type 2 isolates were evaluated for their virulence in pigs and mice. Of these, seven were determined to be highly virulent in pigs on the basis of clinical sign scores and gross pathology and histopathology results. Clinical sign scores correlated with gross pathology and histopathology scores at P equal to 0.004 and P equal to 0.009, respectively. The virulence of highly virulent isolates in pigs compared somewhat with virulence in mice, but the correlation was not significant. No correlation of virulence was noted among the moderately virulent and avirulent isolates in pigs and mice. Chromosomal DNAs from all S. suis isolates were evaluated by PstI, PvuII, EcoRI, and HaeIII restriction enzyme digestion followed by hybridization with a digoxigenin-11-dUTP-labeled cDNA probe transcribed from 16S and 23S rRNAs from Escherichia coli. The hybridization patterns (ribotypes) varied depending upon the enzyme used, but a significant number of isolates determined to be highly virulent in pigs had unique hybridization patterns compared with those of the moderately virulent and avirulent isolates (P = 0.002). In addition, hemolysin activity showed a high correlation to virulence (P = 0.00008) and ribotype (P =...Continue Reading

References

Oct 1, 1992·Journal of Clinical Microbiology·P Gerner-Smidt
Apr 1, 1991·Journal of Clinical Microbiology·J D MogollonP P Cleary
Jun 1, 1990·Journal of Bacteriology·M JacquesR Higgins
Sep 1, 1990·Journal of Clinical Microbiology·M GottschalkR Higgins
Sep 1, 1986·Annales De L'Institut Pasteur. Microbiology·F Grimont, P A Grimont
Apr 1, 1972·The Journal of Infectious Diseases·B R Andersen, D E Van Epps
Jan 1, 1995·Microbiology·M G GottschalkJ D Dubreuil
Oct 1, 1994·Epidemiology and Infection·C G MwanikiD J Hampson
Jul 1, 1994·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·R Y ReamsT L Bowersock
May 1, 1994·Journal of Clinical Microbiology·I FederJ Staats
Apr 1, 1993·Livestock Production Science·F MadecY Leforban

❮ Previous
Next ❯

Citations

Mar 13, 2002·Journal of Bacteriology·Daisuke TakamatsuTsutomu Sekizaki
Sep 26, 2001·Applied and Environmental Microbiology·R BrousseauS M Hemmingsen
May 10, 2005·Revista Do Instituto De Medicina Tropical De São Paulo·Adrienny T R CostaFrancisco A Uzal
Mar 10, 2001·Clinical and Diagnostic Laboratory Immunology·O OkwumabuaP G Reddy
Apr 9, 2005·Clinical and Diagnostic Laboratory Immunology·Ogi Okwumabua, Sharmila Chinnapapakkagari
Jun 8, 2001·Veterinary Microbiology·L O Andresen, C Tegtmeier
Jan 15, 2000·Journal of Clinical Microbiology·M GottschalkS Quessy
Jun 7, 2003·Journal of Clinical Microbiology·Ana I VelaJosé F Fernández-Garayzábal
Feb 5, 2002·Journal of Clinical Microbiology·Florence Berthelot-HéraultMarylène Kobisch
Feb 24, 2007·The Lancet Infectious Diseases·Zhao-Rong LunXing-Quan Zhu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.