Use of semen quality scores to predict pregnancy rates in couples undergoing intrauterine insemination with donor sperm

Fertility and Sterility
Shyam S R AllamaneniAshok Agarwal

Abstract

To establish semen quality scores in a population of sperm donors and determine whether the scores can be used to predict pregnancy rates after donor insemination. Retrospective study. Infertility clinic at a tertiary care teaching hospital between 1993-2001. One hundred eleven women who underwent IUI with sperm from 27 anonymous donors. None. The semen analysis results before freezing and after thawing were analyzed, and overall donor insemination semen quality (DI-SQ) and donor insemination relative quality (DI-RQ) scores were calculated. After adjusting for female characteristics, the scores were compared with samples that did and did not result in pregnancy. Of 111 patients, 70 had at least one pregnancy, and 60 had at least one live birth, with a mean of 6.52 +/- 4.67 IUI cycles per patient. Five significant risk factors for low pregnancy and live birth rates were identified: female infertility factor, positive laparoscopy, older maternal age, low number of previous births, and lack of ovulatory stimulation. After adjusting for these factors, both prefreeze and postthaw DI-SQ scores were statistically significantly associated with IUI live birth rates. Using only the samples with a DI-SQ score of >110 doubled the expected ...Continue Reading

Citations

Sep 21, 2013·Journal of Assisted Reproduction and Genetics·Wang RuixueLiu Ruizhi
Apr 11, 2008·International Journal of Andrology·Thomas FreourPaul Barriere
Mar 2, 2010·Journal of Midwifery & Women's Health·Elisabeth Boo MarkusJudith Jones

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