Use of serial measurements of peritoneal fluid lactate concentration to identify strangulating intestinal lesions in referred horses with signs of colic

Journal of the American Veterinary Medical Association
John G Peloso, Noah D Cohen

Abstract

To determine the value of serial measurements of peritoneal fluid lactate concentration (PFL) for detecting strangulating intestinal lesions (SLs) in referred horses with signs of colic. Retrospective cohort study. 94 horses with signs of colic. Medical records of horses evaluated between September 2006 and February 2010 because of signs of colic were reviewed. All included horses had ≥ 2 peritoneal fluid samples collected, including one at admission and another within 1 to 6 hours after admission. Of the 94 horses, 26 were assigned to the SL group on the basis of findings at surgery or necropsy and 68 were assigned to the nonstrangulating intestinal lesion group because their signs of colic resolved with medical management. Peritoneal fluid lactate concentration was measured by use of a handheld lactate monitor. Data were analyzed by use of univariable and multivariable logistic regression analysis. PFL at admission > 4 mmol/L, an increase in PFL over time, and especially an increase in PFL over time in horses with a PFL < 4 mmol/L at admission (OR, 62; sensitivity, 95%; specificity, 77%) were significant predictors of horses with an SL. Serially determined PFL was a strong predictor for differentiating horses with SLs from ho...Continue Reading

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Citations

Jul 14, 2014·The Veterinary Clinics of North America. Equine Practice·Vanessa L Cook, Diana M Hassel
Jan 16, 2015·Journal of Veterinary Emergency and Critical Care·Rolfe M RadcliffeThomas J Divers
Jul 8, 2016·Journal of Veterinary Emergency and Critical Care·Tina H PihlStine Jacobsen
Mar 14, 2018·Journal of Veterinary Emergency and Critical Care·Patricia G RosensteinDez Hughes
Dec 28, 2018·Veterinary Surgery : VS·Isabelle KilcoyneJulie E Dechant
Apr 1, 2020·Journal of the American Veterinary Medical Association·Isabelle KilcoyneJulie E Dechant
Jan 26, 2021·Mediators of Inflammation·Ann Kristin BartonHeidrun Gehlen
Nov 8, 2021·Equine Veterinary Journal·Maria L Rodríguez-PozoEduard Jose-Cunilleras

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