PMID: 8957793Nov 1, 1996Paper

Use of subvoxel registration and subtraction to improve demonstration of contrast enhancement in MRI of the brain

Neuroradiology
W L CuratiG M Bydder

Abstract

To assess the potential of registration of images before and after contrast medium for improving the demonstration of contrast enhancement, we compared conventional 2D T1-weighted spin-echo images with precisely registered 3D volume images and subtraction images derived from them in 2 normal subjects and 30 patients with a variety of brain disease. The volume images were registered to subvoxel accuracy using a rigid body translation and rotation, sinc interpolation and a least-squares fit; subtraction images were obtained from these. Normal contrast enhancement was demonstrated better with positionally registered volume and subtraction images than with conventional images in the meninges, ependyma, diploic veins, scalp, skin, orbit and sinuses. Abnormal enhancement was seen better in meningeal disease, multiple sclerosis and tumours as well as on follow-up studies. Subvoxel registration of images before and after contrast medium may be of considerable value in the recognition of contrast enhancement where there are small changes, or where the changes affect tissues with high or low baseline signal values. The technique also appears likely to be of value in demonstrating contrast enhancement in tissues at interfaces and at other...Continue Reading

Citations

Oct 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·N A ThackerE Vokurka
Dec 20, 2011·Neuroradiology·Xavier LladóAlex Rovira
Mar 5, 2002·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Alan JacksonA Emmen
Dec 13, 2006·Neuropsychology Review·Andrew LeeArgye E Hillis
Jan 29, 2009·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Khalil JivrajAnil Walji
Jun 1, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·E K KeenihanC R Lamb
May 17, 2014·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Christopher R LambStephen Frean
Oct 7, 2003·Annual Review of Biomedical Engineering·Arthur W Toga, Paul M Thompson

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