Use of symptoms and risk factors to predict acute otitis media in infants

International Journal of Pediatric Otorhinolaryngology
David P McCormickTasnee Chonmaitree

Abstract

Infants and children with upper respiratory tract infection (URI) often have concurrent acute otitis media (AOM). Young infants have fewer specific symptoms than older children. The purpose of this study was to evaluate the usefulness of symptoms and other risk factors in predicting the presence of AOM in infants. Healthy infants, age less than four weeks, were enrolled and followed prospectively for up to age one year. Infants were scheduled for a research visit when their parents noted the onset of symptoms. At each URI visit, parents first reported the severity of symptoms. An investigator then diagnosed the presence or absence of concurrent AOM. Risk factors and symptom scores for infants with and without AOM were studied. Infants (N=193, mean age at first URI 3.9±2.5 months) experienced 360 URI episodes and 63 AOM events. Symptoms consisting of fever, earache, poor feeding, restless sleep, and irritability together (ETG-5) were statistically associated with the prediction of AOM (P=0.006). A multiple variable statistical model (J-Score) that included day care attendance, age, severity of cough and earache best predicted AOM (P<0.001), with 95% specificity. Both ETG-5 and J-score yielded relatively low sensitivity for AOM p...Continue Reading

References

Jun 3, 1999·Pediatrics·K A DalyG S Giebink
Sep 23, 2000·The Pediatric Infectious Disease Journal·M E Pichichero
Oct 3, 2003·Pediatrics·David P McCormickTasnee Chonmaitree
Feb 8, 2006·The Pediatric Infectious Disease Journal·Norman R FriedmanKokab A Saeed
Feb 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tasnee ChonmaitreeKelly J Henrickson
Dec 17, 2008·The Pediatric Infectious Disease Journal·Nader ShaikhLisa M Zoffel
Aug 17, 2010·The Pediatric Infectious Disease Journal·Stella U KaluTasnee Chonmaitree
Mar 29, 2011·International Journal of Pediatric Otorhinolaryngology·David P McCormickTasnee Chonmaitree
Apr 8, 2011·Clinical Pediatrics·Janet R CaseyMichael E Pichichero
Feb 27, 2013·Pediatrics·Allan S LieberthalDavid E Tunkel
Apr 23, 2013·International Journal of Pediatric Otorhinolaryngology·Patricia SommerfleckHoracio Lopardo
Nov 28, 2013·JAMA Pediatrics·Tal MaromTasnee Chonmaitree
Jan 1, 2014·International Journal of Pediatric Otorhinolaryngology·Colin BarberHarvey Coates
Sep 11, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tasnee ChonmaitreeRichard B Pyles
Nov 19, 2014·Pediatrics·Michael J LoeffelholzTasnee Chonmaitree

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Citations

Jan 31, 2002·The Annals of Pharmacotherapy·Catherine M RoeBrenda R Motheral
Dec 27, 2019·The Pediatric Infectious Disease Journal·Elena ChiappiniUNKNOWN and the Italian Panel for the Management of Acute Otitis Media in Children
Dec 27, 2019·The Pediatric Infectious Disease Journal·Paola MarchisioElena Chiappini
Jan 9, 2018·Global Pediatric Health·Saurabh TalathiYekaterina Sitnitskaya
Dec 21, 2020·Sleep Medicine Reviews·Lourdes M DelRossoUNKNOWN International Restless Legs Syndrome Study Group (IRLSSG)

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