Use of tetrahydrozoline for chemical submission

Forensic Science International : Synergy
Matthew E Stillwell, Joseph J Saady

Abstract

We report two cases of drug-facilitated sexual assault which presented with CNS depression rendering the victims vulnerable to sexual assault and unable to recall the events surrounding the crimes. In each tetrahydrozoline (THZ) was quantified. Case #1 ingested an unknown amount of eye drops containing THZ mixed with alcoholic beverages. Case #1 presented to the emergency department (ED) approximately 7h after reportedly being sexually assaulted and was without symptoms in the ED. Earlier reports from individuals who saw her indicated the victim to be "heavily intoxicated". Case #2 also ingested an unknown amount of eye drops containing THZ mixed with alcoholic beverages. Case #2 presented to an ED without symptoms approximately 23h after reportedly being sexually assaulted. Urine obtained from both cases was assessed for THZ concentrations using gas-chromatography-mass spectrometry. Case #1 had a 0.15g% (by weight by volume) urine ethanol concentration and a urinary THZ concentration of 1.481ng/ml, approximately 7h after ingestion. Case #2 was negative for ethanol but had a urine THZ concentration of 108ng/ml at 23h post-ingestion. Few case reports have been published documenting the use of THZ to facilitate sexual assault. We...Continue Reading

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Citations

Apr 25, 2014·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Suad A Al-AbriKent R Olson
Mar 29, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·J A Lowry, J T Brown
Mar 28, 2021·Journal of Forensic and Legal Medicine·M G GarcíaI Legaz
May 14, 2021·BMJ Case Reports·Omar AfifyOmar Saaed

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