PMID: 10600751Dec 22, 1999

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic

Science
Eefjan BreukinkBen de Kruijff

Abstract

Resistance to antibiotics is increasing in some groups of clinically important pathogens. For instance, high vancomycin resistance has emerged in enterococci. Promising alternative antibiotics are the peptide antibiotics, abundant in host defense systems, which kill their targets by permeabilizing the plasma membrane. These peptides generally do not act via specific receptors and are active in the micromolar range. Here it is shown that vancomycin and the antibacterial peptide nisin Z use the same target: the membrane-anchored cell wall precursor Lipid II. Nisin combines high affinity for Lipid II with its pore-forming ability, thus causing the peptide to be highly active (in the nanomolar range).

Citations

Aug 10, 2000·Biopolymers·Ingolf F Nes, Helge Holo
Aug 10, 2000·Biopolymers·A GuderH G Sahl
Dec 20, 2002·Biopolymers·Yechiel Shai
Dec 20, 2002·Biopolymers·Dewey G McCaffertyWenkai Li
Jul 8, 2005·Applied Microbiology and Biotechnology·Stefan HeinzmannTorsten Stein
Jul 21, 2010·Applied Microbiology and Biotechnology·Takeshi ZendoKenji Sonomoto
May 7, 2010·Journal of Industrial Microbiology & Biotechnology·Eric Cundliffe, Arnold L Demain
Aug 29, 2012·Biotechnology Letters·Xiulan Li, Daniel J O'Sullivan
Jun 7, 2011·Biomolecular NMR Assignments·Nina Alexandra ChristJens Wöhnert
Apr 15, 2004·Current Opinion in Biotechnology·Ingolf F Nes, Ola Johnsborg
Jun 7, 2005·FEMS Microbiology Reviews·Jan KokOscar P Kuipers
May 3, 2005·International Journal of Food Microbiology·R Bauer, L M T Dicks
Aug 16, 2005·Journal of the American Society for Mass Spectrometry·Anne J KleinnijenhuisRon M A Heeren
Jul 20, 2002·Biochemical and Biophysical Research Communications·Lili XieWilfred A van der Donk
Apr 23, 2003·Biochemical and Biophysical Research Communications·Carsten CorveyKarl-Dieter Entian
Oct 4, 2002·Il Farmaco·Anja HoffmannHans-Georg Sahl
Jun 11, 2002·Journal of Molecular Biology·Daili Jacqueline Aguilar NetzHans-Georg Sahl
Jan 5, 2002·International Journal of Food Microbiology·J ClevelandMichael L Chikindas
Apr 6, 2002·International Journal of Food Microbiology·Steeg P F ter, J E Ueckert
Oct 18, 2002·International Journal of Food Microbiology·R P RossColin Hill
May 12, 2001·FEMS Microbiology Reviews·Olivia McAuliffeColin Hill
Nov 9, 2002·Biochimie·Sylvie GarneauJohn C Vederas
Feb 11, 2004·FEMS Microbiology Letters·Olli KoponenPer E J Saris
Feb 24, 2001·Research in Microbiology·Oscar P KuipersJan Kok
Jun 26, 2001·Research in Microbiology·Michael Otto, F Götz
Jul 25, 2000·Molecular Medicine Today·Y T TanI A McKay
May 29, 2000·Current Opinion in Chemical Biology·R W Jack, G Jung
Aug 26, 2000·Current Opinion in Chemical Biology·K Bush, M Macielag
Jun 14, 2000·Current Opinion in Microbiology·W N KoningsBert Poolman
Jun 24, 2008·Biochemistry·Gregory C PattonWilfred A van der Donk
Aug 19, 2011·Journal of the American Chemical Society·Wei LiuJohn C Vederas
Jan 28, 2012·Journal of the American Chemical Society·Avena C RossJohn C Vederas
Dec 16, 2006·The Journal of Organic Chemistry·Wilfred A van der Donk
Nov 15, 2011·Nature Nanotechnology·A RamanS Antoranz Contera
Mar 15, 2006·Nature Reviews. Drug Discovery·Eefjan Breukink, Ben de Kruijff
Oct 6, 2005·Nature Reviews. Microbiology·Paul D CotterR P Ross
Jun 17, 2006·Nature Reviews. Microbiology·Andreas Peschel, Hans-Georg Sahl
May 23, 2009·Molecular BioSystems·Richard M Epand, Raquel F Epand
Apr 26, 2002·Molecular Microbiology·Torsten SteinKarl-Dieter Entian
Mar 21, 2012·Proceedings of the National Academy of Sciences of the United States of America·Neha GargWilfred A van der Donk
Jun 27, 2012·Proceedings of the National Academy of Sciences of the United States of America·Yvonne Maria te WelscherEefjan Breukink
Jul 31, 2009·The Journal of Biological Chemistry·Gang WeiWuyuan Lu
Jan 25, 2012·The Journal of Biological Chemistry·Marzena PazgierWuyuan Lu
May 11, 2012·The Journal of Biological Chemistry·Mohsen RajabiWuyuan Lu
Aug 21, 2012·The Journal of Biological Chemistry·Nina Alexandra ChristJens Wöhnert
Jul 10, 2001·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Anne GravesenSusanne Knøchel
Mar 22, 2012·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Anna MüllerTanja Schneider
May 28, 2009·Antimicrobial Agents and Chemotherapy·Fuminori YoneyamaKenji Sonomoto
Jun 30, 2010·Antimicrobial Agents and Chemotherapy·Raquel F EpandRichard M Epand
Sep 10, 2009·Antimicrobial Agents and Chemotherapy·Thijs R H M KouwenJan Maarten van Dijl
Sep 24, 2008·Antimicrobial Agents and Chemotherapy·Ian M GutSteven R Blanke
Aug 31, 2011·Antimicrobial Agents and Chemotherapy·Aline Dias PaivaHilario C Mantovani
Jun 5, 2013·Antimicrobial Agents and Chemotherapy·Mengqi LiKenji Sonomoto
Sep 12, 2012·Antimicrobial Agents and Chemotherapy·Diana WolfThorsten Mascher
Feb 2, 2011·Antimicrobial Agents and Chemotherapy·Fuminori YoneyamaKenji Sonomoto
Nov 15, 2007·Antimicrobial Agents and Chemotherapy·Judicaël ParisotBoyan B Bonev
Dec 3, 2008·Antimicrobial Agents and Chemotherapy·Jean-Yves F DuboisJan Maarten van Dijl
Mar 11, 2009·Antimicrobial Agents and Chemotherapy·Zhizeng SunLiandong Huan
Jun 10, 2009·Antimicrobial Agents and Chemotherapy·Sikder M AsaduzzamanKenji Sonomoto
Apr 14, 2010·Antimicrobial Agents and Chemotherapy·Yvonne Maria te WelscherEefjan Breukink
Mar 30, 2006·Antimicrobial Agents and Chemotherapy·Raquel R BonelliI Wiedemann
Mar 30, 2006·Antimicrobial Agents and Chemotherapy·Randal EckertWenyuan Shi
Apr 28, 2006·Antimicrobial Agents and Chemotherapy·Naomi E KramerOscar P Kuipers
Jun 10, 2008·Applied and Environmental Microbiology·Beatriz MartínezI Wiedemann
Mar 5, 2013·Applied and Environmental Microbiology·Ainhoa Revilla-GuarinosManuel Zúñiga
Sep 8, 2006·Applied and Environmental Microbiology·Sikder M AsaduzzamanKenji Sonomoto
Sep 16, 2008·Applied and Environmental Microbiology·Anneke KuipersGert N Moll
Nov 18, 2008·Applied and Environmental Microbiology·Fuminori YoneyamaKenji Sonomoto
Dec 31, 2008·Applied and Environmental Microbiology·Shawanda Wilson-StanfordLeif Smith
Jan 18, 2011·Applied and Environmental Microbiology·Sebastian W FuchsKarl-Dieter Entian
Jan 31, 2007·Applied and Environmental Microbiology·Rick RinkGert N Moll
Jun 6, 2006·Applied and Environmental Microbiology·Paul D CotterR P Ross
Mar 23, 2011·Applied and Environmental Microbiology·Morten KjosDzung B Diep
Sep 6, 2011·Applied and Environmental Microbiology·Ana Belén CampeloBeatriz Martínez
Feb 7, 2001·Applied and Environmental Microbiology·Hilario C Mantovani, James B Russell
Oct 31, 2002·Applied and Environmental Microbiology·Daili Jacqueline Aguilar NetzHans-Georg Sahl
Dec 3, 2004·Applied and Environmental Microbiology·Dag Anders BredeHelge Holo
May 7, 2004·Applied and Environmental Microbiology·Jennifer Cleveland McEntireThomas J Montville
Jun 9, 2004·Applied and Environmental Microbiology·Anja HoffmannHans-Georg Sahl
Apr 7, 2006·Applied and Environmental Microbiology·I WiedemannBeatriz Martínez
Jun 19, 2003·Journal of Bacteriology·Els van den Brink-van der LaanBen de Kruijff
May 6, 2004·Journal of Bacteriology·I WiedemannHans-Georg Sahl
Jan 9, 2003·Journal of Clinical Microbiology·Longzhu CuiKeiichi Hiramatsu
May 18, 2007·Annual Review of Microbiology·Joanne M Willey, Wilfred A van der Donk
Apr 29, 2008·Annual Review of Phytopathology·Jose F MarcosBelén López-García
Sep 26, 2012·The Journal of Clinical Investigation·Connie TamSuzanne M J Fleiszig
Oct 30, 2009·BMC Microbiology·María J Grande BurgosOscar P Kuipers
May 24, 2006·Bioscience, Biotechnology, and Biochemistry·Hiroshi Yoneyama, Ryoichi Katsumata
Jul 7, 2012·PloS One·Christopher J ArnuschEefjan Breukink
Apr 22, 2014·Antonie van Leeuwenhoek·Brant R Johnson, Todd R Klaenhammer
Apr 1, 2014·The Journal of Microbiology·Morris O MakobongoD Scott Merrell
Jul 3, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·K V R ReddyR D Yedery
Oct 31, 2013·The Journal of Antibiotics·Neha GargWilfred A van der Donk
Oct 4, 2013·Immunotherapy·Cesar Enrique Rivas-SantiagoBruno Rivas-Santiago
Oct 15, 2013·International Journal of Medical Microbiology : IJMM·F GötzMartin Schlag
Oct 12, 2007·Future Microbiology·Nathaniel I Martin, Eefjan Breukink
May 21, 2013·Future Medicinal Chemistry·Jianmin Gao, Hong Zheng
May 31, 2008·Nanomedicine·Iftach Yacoby, Itai Benhar
Jan 9, 2010·Bioscience, Biotechnology, and Biochemistry·Fuminori YoneyamaKenji Sonomoto
Dec 21, 2006·Proceedings of the National Academy of Sciences of the United States of America·Alexander J HydeBoyan B Bonev
Sep 23, 2014·BioMed Research International·Thomas EbenhanMike Machaba Sathekge
Oct 6, 2014·Current Opinion in Chemical Biology·Le Zhao, Wuyuan Lu
Jul 12, 2014·PloS One·Zainab AlKhatibSander H J Smits
Apr 13, 2002·Organic Letters·Hao Zhou, Wilfred A van der Donk
Nov 14, 2000·Organic Letters·N M OkeleyWilfred A van der Donk
Jul 23, 2013·Biochemistry·André AbtsLutz Schmitt
May 17, 2011·Cellular and Molecular Life Sciences : CMLS·Raquel F EpandRichard M Epand
Oct 31, 2012·Cellular and Molecular Life Sciences : CMLS·Riadh HammamiI Fliss
Nov 28, 2007·Expert Review of Anti-infective Therapy·John D F Hale, Robert E W Hancock
Jun 1, 2009·Expert Opinion on Drug Discovery·Jose F Marcos, Mónica Gandía
Feb 1, 2011·Expert Opinion on Drug Discovery·Mohammed M Al-Mahrous, Mathew Upton
Jun 12, 2012·Expert Opinion on Drug Discovery·Manuel Montalbán-LópezOscar P Kuipers
Feb 19, 2016·Scientific Reports·Sam MulhollandJonathan D Hirst
Feb 11, 2016·Applied Microbiology and Biotechnology·Patricia Alvarez-SieiroOscar P Kuipers
Feb 24, 2016·Frontiers in Cell and Developmental Biology·Liang ZhouOscar P Kuipers
Nov 21, 2015·Journal of Medicinal Chemistry·Izidor SosicStanislav Gobec
Nov 7, 2001·Journal of Peptide Science : an Official Publication of the European Peptide Society·P StaubitzRalph W Jack
Jan 17, 2012·Progress in Lipid Research·Vitor TeixeiraMargarida Bastos
Mar 1, 2016·Nature Communications·Colin C KietzmanElaine I Tuomanen
Mar 2, 2011·Biochemical Pharmacology·Adeline DerouauxMohammed Terrak
Jun 16, 2010·International Journal of Antimicrobial Agents·James CarrollJim O'Mahony
May 18, 2010·Journal of Bioscience and Bioengineering·Masayuki TaniguchiTakaaki Tanaka
Apr 27, 2011·ACS Chemical Biology·Ian M GutWilfred A van der Donk
Apr 25, 2012·Journal of the American Chemical Society·Patrick J Knerr, Wilfred A van der Donk
Oct 19, 2011·Journal of the American Chemical Society·Trent J OmanWilfred A van der Donk
Apr 28, 2009·Journal of Bioscience and Bioengineering·Sikder M Asaduzzaman, Kenji Sonomoto
Nov 15, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Ben de KruijffEefjan Breukink
Jun 1, 2014·Biochimica Et Biophysica Acta·Konstantin AndreevDavid Gidalevitz
Sep 13, 2015·Applied Microbiology and Biotechnology·Seiichi TaguchiHiromi Matsusaki
Apr 17, 2013·Scientific Reports·Anton ChugunovRoman Efremov
Apr 28, 2005·Molecular Microbiology·Torsten Stein
Mar 8, 2003·Molecular Microbiology·Torsten SteinKarl-Dieter Entian
Feb 18, 2009·Chembiochem : a European Journal of Chemical Biology·Matthew R LevengoodWilfred A van der Donk
Jan 29, 2009·Chembiochem : a European Journal of Chemical Biology·Vincent van DamEefjan Breukink
Jun 15, 2006·Molecular Microbiology·Eefjan Breukink
Aug 19, 2006·Angewandte Chemie·G Jung
Apr 12, 2011·Journal of Peptide Science : an Official Publication of the European Peptide Society·Richard M Epand, Raquel F Epand
Dec 16, 2011·Immunological Reviews·Robert I Lehrer, Wuyuan Lu
Nov 30, 2012·Biopolymers·Annia AlbaAnselmo J Otero-González
Jan 11, 2013·Annals of the New York Academy of Sciences·Nannette Y Yount, Michael R Yeaman
Sep 12, 2013·Journal of Peptide Science : an Official Publication of the European Peptide Society·Jack C SlootwegDirk T S Rijkers
Jan 19, 2010·Angewandte Chemie·Kathrin MeindlRoderich D Süssmuth
Jul 6, 2014·Angewandte Chemie·Peter M WrightAndrew G Myers
Sep 30, 2008·Biochimica Et Biophysica Acta·Richard M Epand, Raquel F Epand
Jan 25, 2011·Microbial Biotechnology·Lucy H DeeganR P Ross
Mar 12, 2005·Biochimie·Carlos J MinahkRoberto Morero
Nov 3, 2004·Biochimica Et Biophysica Acta·Joachim Seelig
Oct 19, 2006·Journal of Bioscience and Bioengineering·Jun-Ichi NagaoKenji Sonomoto
Dec 17, 2005·Peptides·Lidia Cruz-ChamorroManuel A de Pablo
Oct 18, 2005·International Journal of Antimicrobial Agents·Koichi KuwanoKenji Sonomoto
Jun 26, 2004·Journal of Chemotherapy·A BartoloniF Paradisi
Aug 25, 2005·Current Opinion in Microbiology·Gregory C Patton, Wilfred A van der Donk
May 15, 2015·Bioengineered·Des FieldColin Hill
Nov 20, 2014·Microbiology·Maria do Carmo de Freire BastosOlinda Cabral da Silva Santos
Jan 24, 2015·Biomolecular NMR Assignments·Carolin HackerJens Wöhnert
Apr 7, 2016·Biochimica Et Biophysica Acta·Katerina C NastouStavros J Hamodrakas
Nov 28, 2012·Biochemical Society Transactions·Evelyn M MolloyColin Hill
Nov 28, 2012·Biochemical Society Transactions·Mohammad R IslamKenji Sonomoto
Dec 18, 2007·FEMS Microbiology Reviews·Ahmed BouhssDominique Mengin-Lecreulx
Nov 14, 2006·FEMS Microbiology Reviews·Alain DufourJean-Paul Le Pennec
Jul 31, 2012·International Journal of Pharmaceutics·Subhankari Prasad ChakrabortySomenath Roy
Aug 28, 2012·Bioengineered·Paul D Cotter
Dec 3, 2014·Current Opinion in Structural Biology·Wilfred A van der Donk, Satish K Nair
Oct 14, 2008·Current Opinion in Microbiology·Leif Smith, Jd Hillman
Dec 17, 2009·International Journal of Medical Microbiology : IJMM·Tanja Schneider, Hans-Georg Sahl
Aug 2, 2011·Chemistry & Biology·Juan E VelásquezWilfred A van der Donk
Apr 25, 2012·Biochimica Et Biophysica Acta·Cristina ChamorroRoland J Pieters
Oct 21, 2006·Chemistry & Biology·Champak ChatterjeeWilfred A van der Donk
Feb 15, 2003·Biochimica Et Biophysica Acta·Edmund R S KunjiBert Poolman
Mar 15, 2015·Frontiers in Microbiology·Rustem KhusainovOscar P Kuipers
Jan 13, 2015·Critical Reviews in Food Science and Nutrition·E KhanniriR Mohammad
Sep 29, 2004·FEMS Microbiology Letters·Naomi E KramerEefjan Breukink
Jul 28, 2010·FEMS Microbiology Letters·John W SchmidtDewey G McCafferty
Sep 17, 2005·FEMS Microbiology Letters·Beatriz Martínez, Ana Rodríguez
Nov 9, 2014·Applied and Environmental Microbiology·Sophie M BochmannKarl-Dieter Entian
Oct 22, 2014·Antimicrobial Agents and Chemotherapy·Rebeca MartínJuan E Suarez
May 11, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Hwang-Soo JooMichael Otto
Dec 19, 2015·Journal of Applied Microbiology·J M ShinY L Kapila
Jul 5, 2016·Frontiers in Cell and Developmental Biology·Rafi RashidKimberly A Kline
Aug 3, 2016·Probiotics and Antimicrobial Proteins·D DriderMichael L Chikindas
Aug 9, 2016·Applied Microbiology and Biotechnology·Hannah Ulm, Tanja Schneider
Aug 17, 2016·Scientific Reports·Abdelahhad BarbourKoshy Philip
Aug 11, 2016·Biochemistry·Samuel Furse, David J Scott
Apr 21, 2009·Methods in Enzymology·Bo LiWilfred A van der Donk
Sep 4, 2016·FEMS Microbiology Reviews·Manuel Montalbán-LópezOscar P Kuipers
Nov 6, 2013·Proceedings of the National Academy of Sciences of the United States of America·Kumaravel KandaswamyKimberly A Kline
Oct 25, 2016·PloS One·Jamal ChauhanErik P H de Leeuw
Jan 31, 2017·Chemical Reviews·Lindsay M RepkaWilfred A van der Donk
Jul 5, 2017·Natural Product Reports·Anna MüllerTanja Schneider
Sep 14, 2004·Nature Structural & Molecular Biology·Shang-Te D HsuNico A J van Nuland
Apr 5, 2013·The American Journal of Gastroenterology·Ahmad H AliRoger D Smalligan
May 20, 2018·Applied and Environmental Microbiology·Mengxin Geng, Leif Smith
Dec 8, 2004·Journal of Leukocyte Biology·Hans-Georg SahlAlessandro Tossi
Aug 8, 2018·FEMS Microbiology Reviews·Jeella Z AcedoMarco J van Belkum
May 14, 2017·Applied and Environmental Microbiology·Jerome EscanoLeif Smith
Mar 15, 2015·Applied and Environmental Microbiology·Shradha Basi-ChipaluGabriele Bierbaum
Mar 20, 2015·Microbiology and Molecular Biology Reviews : MMBR·Lorraine A DraperR P Ross
Jan 22, 2015·Journal of Bacteriology·Jerome EscanoLeif Smith
Apr 15, 2015·Antimicrobial Agents and Chemotherapy·Menno B TolDirk-Jan Scheffers
Oct 20, 2018·Applied Microbiology and Biotechnology·Piyush BaindaraVishakha Grover
Jan 12, 2019·Physical Chemistry Chemical Physics : PCCP·Ashutosh PrinceMohammed Saleem
Sep 27, 2018·Molecular Plant-microbe Interactions : MPMI·Da-Ran KimYoun-Sig Kwak
Jan 29, 2009·Biopolymers·Fateh S Nandel, Tammanna R Sahrawat
Apr 7, 2019·Applied and Environmental Microbiology·Christoph GeigerKarl-Dieter Entian
Jul 28, 2012·Prikladnaia biokhimiia i mikrobiologiia·L G StoianovaA I Netrusov
May 31, 2019·Physical Chemistry Chemical Physics : PCCP·Rudramani PokhrelPrem P Chapagain
Jun 9, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ahmad MassarwehStuart E H Moore
Mar 15, 2014·The Journal of Biological Chemistry·Daniela MünchHans-Georg Sahl
May 16, 2019·Microbiology·Fernanda Godoy-SantosHilario C Mantovani
Jun 13, 2017·Macromolecular Bioscience·Sithara S NairKenneth J Wynne
Dec 13, 2006·Microbiology·Timo M Takala, Per E J Saris
Sep 25, 2019·Viruses·Susana EscobedoBeatriz Martínez
Mar 23, 2019·Biomedical Materials·Wei QuWei Zhang
Mar 29, 2003·The Journal of Biological Chemistry·Eefjan BreukinkBen de Kruijff
Dec 4, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Boyan B BonevAnthony Watts
Jun 5, 2020·FEMS Microbiology Reviews·Beatriz MartínezMarie-Pierre Chapot-Chartier
Feb 13, 2018·Experimental and Therapeutic Medicine·Lijun HuoJia Liu
Dec 1, 2012·Probiotics and Antimicrobial Proteins·Clara RocesBeatriz Martínez
Apr 1, 2005·Journal of Biomolecular Screening·S M SolapureS M De Sousa
Oct 25, 2014·The Journal of Biological Chemistry·Andreas EssigMarkus Aebi
Jul 28, 2020·Applied and Environmental Microbiology·Jiaheng LiuJianjun Qiao
Feb 9, 2017·Scientific Reports·Jens ReinersLutz Schmitt
Jul 16, 2017·Applied and Environmental Microbiology·Christoph GeigerKarl-Dieter Entian
Jul 1, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hannah L BoltSteven L Cobb
Feb 7, 2019·Chembiochem : a European Journal of Chemical Biology·João Medeiros-SilvaMarkus Weingarth
Aug 21, 2019·Frontiers in Microbiology·Shilja ChoyamRajagopal Kammara
Jun 3, 2020·Scientific Reports·Irina PaninaAnton Chugunov
Oct 1, 2016·Proceedings of the National Academy of Sciences of the United States of America·Stephen A CochraneJohn C Vederas
Dec 17, 2018·Archives of Microbiology·Alexey S Vasilchenko, Alexander V Valyshev
Apr 19, 2019·Psychopharmacology·Julia Aresti Sanz, Sahar El Aidy
Sep 29, 2018·Nature Communications·João Medeiros-SilvaMarkus Weingarth
Aug 4, 2019·World Journal of Microbiology & Biotechnology·Chang-Wook JeonYoun-Sig Kwak
Sep 25, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hiroshi Ogawara
Jun 26, 2020·Frontiers in Microbiology·Marcel LagedrosteLutz Schmitt
Mar 25, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ines GrecoPaul R Hansen
Feb 1, 2019·Scientific Reports·Marcel LagedrosteLutz Schmitt
Sep 21, 2018·Frontiers in Microbiology·Rodney H PerezKenji Sonomoto
Nov 23, 2005·Journal of Food Protection·Beatriz MartínezAna Rodríguez
Jul 28, 2019·International Journal of Medical Microbiology : IJMM·Sandra UnsleberEvi Stegmann
Oct 9, 2018·Biochimica Et Biophysica Acta. Biomembranes·Alice B M LanneBoyan B Bonev
Nov 17, 2020·Frontiers in Cellular and Infection Microbiology·Ann-Britt Schäfer, Michaela Wenzel
Apr 1, 2003·Comprehensive Reviews in Food Science and Food Safety·S Bruin, Th R G Jongen
Jan 15, 2021·Comprehensive Reviews in Food Science and Food Safety·Yanlong CuiXin Lü
Dec 29, 2020·Critical Reviews in Food Science and Nutrition·Silpa S, Rupachandra S
Mar 4, 2020·Biochimica Et Biophysica Acta. Biomembranes·Xiaoqi WangEefjan Breukink

Related Concepts

undecaprenyl diphosphate-(N-acetylglucosaminyl)(1-4)-N-acetylmuramoyl pentapeptide
Nisin Z
Antibiotics
Plasma Membrane
Cell Membrane Permeability
Cell Wall
Dose-Response Relationship, Drug
Membrane Lipids
Fungus Drug Sensitivity Tests
Micrococcus

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.