Use of the finite element method to study the mechanism of spinal cord injury without radiological abnormality in the cervical spine

Spine
Yasuaki ImajoToshihiko Taguchi

Abstract

Three-dimensional C3-C5 and C3-C4 finite element (FE) models were used to analyze biomechanical responses under compression and extension moments. To validate our models against other published FE models and experimental studies and improve our understanding of the mechanism of spinal cord injury without radiologic abnormality (SCIWORA) in cervical spine. The underlying mechanism for SCIWORA remains unclear. We hypothesized that the incidence of SCIWORA was associated with facet joint morphology and bony pincers mechanism. FE models were constructed using data from computed tomography scans of the cervical spine of a healthy young man. The C3-C5 FE models consisted of bony vertebra, articulating facets, and intervertebral disc. Facet surfaces were oriented at 30 degrees , 45 degrees , and 60 degrees from the transverse plane. These models were constrained in all degrees of freedom at the C5 inferior vertebral body and a uniform axial displacement of 1 mm was applied to the superior nodes of C3. Three model versions changed to C3-C4 models with ligaments. The C4 inferior-most bony nodes were constrained, whereas the top of the C3 superior-most bony nodes were left unconstrained. These models were subjected to an axial compressio...Continue Reading

References

Jan 1, 1991·Journal of Biomechanics·M SheaW C Hayes
Jan 1, 1988·Journal of Biomechanics·S P MoroneyG B Andersson
Jul 1, 1982·Journal of Neurosurgery·D Pang, J E Wilberger
Aug 1, 1996·Spine·N YoganandanF A Pintar
Oct 1, 1996·Medical Engineering & Physics·N YoganandanS J Larson
Feb 1, 1997·Journal of Spinal Disorders·S KumaresanS J Larson
Oct 21, 2000·The Journal of Bone and Joint Surgery. British Volume·P KothariR Kerslake
Nov 1, 1951·The Journal of Bone and Joint Surgery. British Volume·A R TAYLOR
Apr 20, 2004·Spine·Adam M PearsonManohar M Panjabi

❮ Previous
Next ❯

Citations

Nov 1, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Honggang GuoXinlong Ma
Nov 12, 2013·Acta Biomaterialia·Snehal S ShetyeChristian M Puttlitz
Jul 19, 2016·Journal of Biomechanical Engineering·Shervin JannesarCarolyn J Sparrey
Dec 2, 2019·Orthopaedics & Traumatology, Surgery & Research : OTSR·David BraugeJérôme Sales de Gauzy
Oct 12, 2021·Journal of Neurological Surgery. Part A, Central European Neurosurgery·Luca PapaveroGregor Schmeiser

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.