USE OF THE ISCHEMIC INDEX ON WIDEFIELD FLUORESCEIN ANGIOGRAPHY TO CHARACTERIZE A CENTRAL RETINAL VEIN OCCLUSION AS ISCHEMIC OR NONISCHEMIC

Retina
Akshay S ThomasS Fekrat

Abstract

To understand the relationship between baseline ischemic index (IsI) values on ultra-widefield fluorescein angiography and classification as ischemic central retinal vein occlusion (CRVO). Single-center retrospective cohort study of CRVO patients imaged using ultra-widefield fluorescein angiography from which IsI values were calculated. An ischemic CRVO was defined as those eyes with an afferent pupillary defect and counting fingers acuity or worse or neovascularization during the first year of follow-up. Logistic regression was performed to characterize the relation between the IsI and clinical outcomes. Sixty eyes of 60 treatment-naive CRVO patients with baseline ultra-widefield fluorescein angiography and ≥1 year of follow-up were identified. Those with an IsI ≥35% were significantly more likely to have an ischemic CRVO during the first year of follow-up than those with an IsI <35% (83.3 vs. 13.9%, odds ratio 111, P < 0.0001). Baseline and final logarithm of the minimum angle of resolution acuity were worse in eyes with an IsI ≥35% (1.18 vs. 0.46, P < 0.001 and 1.26 vs. 0.45, P < 0.001, respectively) despite similar baseline and final central subfield thickness (P = 0.1-0.23). A baseline IsI of ≥35% on ultra-widefield fluore...Continue Reading

References

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Citations

Jul 26, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Melissa Mei Hsia ChanSharon Fekrat
Jun 9, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Delaram MirzaniaSharon Fekrat
May 28, 2020·Investigative Ophthalmology & Visual Science·Adrian AuDavid Sarraf
Aug 24, 2020·The British Journal of Ophthalmology·Aditya VermaSriniVas Sadda
Nov 24, 2019·Ophthalmology·Christina J FlaxelGui-Shuang Ying
Nov 21, 2021·European Journal of Ophthalmology·Weiting An, Jindong Han

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