Use of three-dimensional ultrasound in the detection of breast tumor bed displacement during radiotherapy

International Journal of Radiation Oncology, Biology, Physics
Philip WongKhalil Sultanem

Abstract

To evaluate the feasibility and usefulness of a three-dimensional ultrasound (3D-US) image-guided system in identifying and tracking the tumor bed (TB) for planning and daily localization before radiation delivery for breast cancer. Twenty breast cancer patients underwent two CT scans at the time of simulation and just before their boost. Three-dimensional ultrasound images were acquired immediately after the CT scans, to which the images were automatically fused. Three-dimensional ultrasound images were also acquired immediately before treatment. Spatial and temporal TB differences between CT and US were evaluated. The TB was not visible on US and CT in 1 subject who had and 1 subject who had not received chemotherapy before whole-breast radiotherapy. The mean (SD) TB volume overlap was 78% (14%). The mean centroid position of the TB on CT vs. US differed by 0.1, 0.2, and 0.4 mm in the anterior-posterior, left-right, and superior-inferior directions. The mean (SD) absolute radial displacement of the TB on each fraction from the treatment plan was 10.8 (6.3) mm. The TB was well visualized by US for the majority of patients. Clinically insignificant differences in the displacements calculated by paired CT vs. paired US demonstra...Continue Reading

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Citations

Aug 17, 2011·Ultrasonic Imaging·Yuling ChenJesse T Yen
Feb 2, 2012·International Journal of Breast Cancer·Sophia M Edwards-BennettEleanor E Harris
Jan 12, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·H K LooeK C Willborn
Mar 30, 2016·International Journal of Radiation Oncology, Biology, Physics·Daniel MortonJuanita Crook
Jan 31, 2015·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Hendrik BallhausenMichael Reiner
Jun 29, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·T Jonathan YangSimon N Powell
Dec 14, 2011·Medical Physics·Danilo De LorenzoElena De Momi
Aug 14, 2012·Journal of Medical Imaging and Radiation Oncology·Carmen J HansenBoon H Chua
Jan 11, 2020·Radiation Oncology Journal·Mutlay SayanRuth Heimann
Oct 10, 2021·Radiology and Oncology·Elham PiruzanHojjat Mahani

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