PMID: 9449145Feb 4, 1998Paper

Use of very low-calorie diet in preoperative weight loss: efficacy and safety

Obesity Research
T Pekkarinen, P Mustajoki

Abstract

We report the efficacy of a very low-calorie diet (VLCD)-based weight reduction program in patients with morbid obesity whose elective surgery had been postponed because of being overweight. The safety of weight loss on the immune system will also be evaluated. Thirty patients (mean age, 50 years; weight, 125 kg; BMI, 44 kg/m2) were treated. The program consisted of a 7-week to 24-week VLCD period, supported by individual sessions with a therapist, and of a refeeding period of 1 month before surgery. Two patients discontinued, and the mean weight loss of the remaining 28 patients was 19.6 kg (15% of initial weight). In 23 patients, weight loss was 10% or more of the initial weight. After weight loss, 15 patients underwent surgery, 4 patients did not need an operation, and the remaining 9 patients were not operated on for various reasons. The numbers of circulating leukocytes, neutrophils, basophils, monocytes, CD3+, CD4+, CD8+, and natural killer cells did not change significantly by the ninth week on VLCD or by the end of the program. However, there was a significant (p < 0.05) decrease in the immunoglobulinM serum concentration during the program. In conclusion, a VLCD program is suitable for preoperative weight reduction in ...Continue Reading

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Citations

Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A MartíJ A Martínez
Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·P Mustajoki, T Pekkarinen
Apr 21, 2011·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Fred BrodyMichael Hill
Nov 3, 2005·International Journal of Behavioral Medicine·Hirohito TsuboiOsamu Fukino
Nov 13, 2009·Nutrition Reviews·Rubhana Raqib, Alejandro Cravioto
Nov 30, 2010·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Nawfal W IstfanR Armour Forse
Mar 11, 2006·Biochemical and Biophysical Research Communications·Jenny PalmingMalin Lönn
Feb 16, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K HongD Heber
Dec 30, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Silvia Leite FariaMarina Kiyomi Ito
Apr 18, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C N OchnerF Xavier Pi-Sunyer
Jul 11, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Mikiko WatanabeLucio Gnessi
Aug 10, 2006·The American Journal of Clinical Nutrition·Susan L CollesPaul E O'Brien
Oct 6, 2020·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·S B GriffinM A Palmer

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