Use of yeast cell wall extract as a tool to reduce the impact of necrotic enteritis in broilers

Poultry Science
Shawkat A M'SadeqRobert A Swick

Abstract

The use of a yeast cell wall extract derived from Saccharomyces cerevisiae (Actigen(®)) has been proposed as an alternative to in-feed antibiotics. This experiment was conducted to investigate the efficacy of yeast cell extract as an alternative to zinc bacitracin or salinomycin using a necrotic enteritis challenge model. A feeding study was conducted using 480-day-old male Ross 308 chicks assigned to 48 floor pens. A 2 × 4 factorial arrangement of treatments was employed. The factors were: challenge (- or +) and feed additive (control, zinc bacitracin at 100/50 mg/kg, yeast cell wall extract at 400/800/200 mg/kg, or salinomycin at 60 mg/kg in starter, grower, and finisher, respectively). Diets based on wheat, sorghum, soybean meal, meat and bone meal, and canola meal were formulated according to the Ross 308 nutrient specifications. Birds were challenged using a previously established protocol (attenuated Eimeria spp oocysts) on d 9 and 10(8) to 10(9) Clostridium perfringens (type A strain EHE-NE18) on d 14 and 15). Challenged and unchallenged birds were partitioned to avoid cross contamination. Challenged birds had lower weight gain, feed intake and livability compared to unchallenged birds on d 24 and d 35 (P < 0.05). Birds ...Continue Reading

References

Mar 17, 2001·The Journal of Antimicrobial Chemotherapy·L A Thal, M J Zervos

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Citations

Mar 10, 2016·Avian Diseases·Shawkat A M'SadeqRobert A Swick
Apr 11, 2019·Veterinary Medicine and Science·Mohammed M HashimChristopher A Bailey
May 18, 2019·Foodborne Pathogens and Disease·Elisa SantovitoGiuseppina Avantaggiato
May 18, 2019·Foodborne Pathogens and Disease·Elisa SantovitoGiuseppina Avantaggiato
Feb 26, 2019·3 Biotech·Phatcharin PrayoonthienSuttipun Keawsompong

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