Many cell phenomena that involve shape changes are affected by the intrinsic deformability of the plasma membrane (PM). Far from being a passive participant, the PM is now known to physically, as well as biochemically, influence cell processes ranging from vesicle trafficking to actin assembly. Here we review current understanding of how changes in PM tension regulate cell shape and movement, as well as how cells sense PM tension.
Forward and reverse transduction at the limit of sensitivity studied by correlating electrical and mechanical fluctuations in frog saccular hair cells
Structure and mechanical properties of giant lipid (DMPC) vesicle bilayers from 20 degrees C below to 10 degrees C above the liquid crystal-crystalline phase transition at 24 degrees C
Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers
Insertion of filamin into lipid membranes examined by calorimetry, the film balance technique, and lipid photolabeling
A piconewton force transducer and its application to measurement of the bending stiffness of phospholipid membranes
Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion
A modified micropipette aspiration technique and its application to tether formation from human neutrophils
Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid: high-speed single-molecule tracking of membrane molecules
Continuous membrane-cytoskeleton adhesion requires continuous accommodation to lipid and cytoskeleton dynamics
EFC/F-BAR proteins and the N-WASP-WIP complex induce membrane curvature-dependent actin polymerization
A bond for a lifetime: employing membrane nanotubes from living cells to determine receptor-ligand kinetics
Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility.
Plasma membrane area increases with spread area by exocytosis of a GPI-anchored protein compartment.
ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions.
Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading
Propranolol restricts the mobility of single EGF-receptors on the cell surface before their internalization
Drosophila E-cadherin is required for the maintenance of ring canals anchoring to mechanically withstand tissue growth
Transient membrane localization of SPV-1 drives cyclical actomyosin contractions in the C. elegans spermatheca
Lamellipodial tension, not integrin/ligand binding, is the crucial factor to realise integrin activation and cell migration
Three-dimensional balance of cortical tension and axial contractility enables fast amoeboid migration
Physico-chemical and biological considerations for membrane wound evolution and repair in animal cells
Conversion of nanoscale topographical information of cluster-assembled zirconia surfaces into mechanotransductive events promotes neuronal differentiation
Coarse-grained molecular dynamics studies of the translocation mechanism of polyarginines across asymmetric membrane under tension
The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing
Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems
Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system
Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear
Osmotic Stress Modulates the Balance between Exocytosis and Clathrin-Mediated Endocytosis in Arabidopsis thaliana
Structural Rearrangements in CHO Cells After Disruption of Individual Cytoskeletal Elements and Plasma Membrane
Feedback regulation between plasma membrane tension and membrane-bending proteins organizes cell polarity during leading edge formation
Nanomechanical and topographical imaging of living cells by atomic force microscopy with colloidal probes
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