Useful tests for hepatic encephalopathy in clinical practice

Current Gastroenterology Reports
Eiman Nabi, Jasmohan S Bajaj

Abstract

Hepatic encephalopathy (HE) is a serious complication of liver disease and portosystemic shunting that represents a continuum of neuropsychiatric changes and altered consciousness. It is classified as overt HE (OHE) when clinically apparent or as covert HE (CHE) in its mildest form. Progression of CHE to OHE and its impact of quality of life make its early diagnosis imperative. Several diagnostic techniques ranging from simple clinical scales to sophisticated computerized tests exist, yet diagnosis remains a challenge, due to the time, cost, and personnel involved. Psychometric tests appear promising due to their high sensitivity and low cost, but results are variable depending on age and education. The pros and cons of current diagnostic methods for OHE and CHE are reviewed, along with strategy for CHE testing.

References

Aug 1, 1996·Seminars in Liver Disease·J C Quero, S W Schalm
Jul 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M GroenewegS W Schalm
May 29, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P AmodioA Gatta
Aug 24, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P AmodioJ M Guérit
Apr 4, 2000·The Journal of Head Trauma Rehabilitation·J WrightP O'Hare
May 15, 2001·Journal of Gastroenterology and Hepatology·A DasS R Naik
Jun 9, 2001·European Journal of Gastroenterology & Hepatology·F KullmannJ Schölmerich
Jul 4, 2001·Journal of Hepatology·K WeissenbornH Hecker
Dec 1, 2001·Metabolic Brain Disease·H Schomerus, W Hamster
Mar 1, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Peter FerenciAndres T Blei
Mar 15, 2003·The American Journal of Medicine·Janus P OngKevin D Mullen
Nov 24, 2004·Metabolic Brain Disease·Sara MontagneseMarsha Y Morgan
Mar 22, 2005·Journal of Hepatology·María OrtizJuan Córdoba
Aug 26, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P AmodioJ M Guerit
Dec 19, 2006·Transplantation Proceedings·T MeyerM Abouljoud
Jan 24, 2007·Journal of Hepatology·Sara MontagneseMarsha Y Morgan
Feb 7, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Scott MooneyUNKNOWN UCSD Hepatology Neurobehavioral Research Program
Feb 28, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jasmohan Singh BajajKia Saeian
Mar 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Manuel Romero-GómezVicente Felipo
Jul 21, 2007·The American Journal of Gastroenterology·Jasmohan S BajajKia Saeian
Aug 22, 2007·Digestive Diseases and Sciences·Tarek I HassaneinWilliam Perry
Sep 5, 2007·Alimentary Pharmacology & Therapeutics·M OrtizJ Guardia
Jul 3, 2008·World Journal of Gastroenterology : WJG·Jasmohan S Bajaj
Aug 30, 2008·Gastroenterology·Jasmohan S BajajKia Saeian
Dec 19, 2008·Expert Review of Gastroenterology & Hepatology·Jasmohan S Bajaj
Mar 12, 2009·The American Journal of Gastroenterology·Jasmohan S BajajKia Saeian
Mar 24, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Christopher RandolphUNKNOWN International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN)
Aug 19, 2009·Gastroenterology·Gerald KircheisDieter Häussinger
Sep 30, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jasmohan S BajajArun J Sanyal
Dec 17, 2009·Alimentary Pharmacology & Therapeutics·J S Bajaj
Mar 26, 2010·The New England Journal of Medicine·Nathan M BassWilliam P Forbes
May 1, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Ewa WunschPiotr Milkiewicz
May 18, 2010·Gastroenterology·Piero AmodioOliviero Riggio
Sep 8, 2010·Annals of Internal Medicine·Jan Albrecht
Oct 7, 2010·Current Gastroenterology Reports·Jennifer Y Montgomery, Jasmohan S Bajaj
Dec 15, 2010·Journal of Hepatology·Juan Córdoba
Feb 11, 2011·Alimentary Pharmacology & Therapeutics·J S BajajUNKNOWN International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN)
Jul 8, 2011·Liver International : Official Journal of the International Association for the Study of the Liver·Ravi K Prakash, Kevin D Mullen

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Citations

Jul 22, 2015·Clinics in Liver Disease·John M Vierling
Oct 29, 2019·The American Journal of Gastroenterology·Mona Haj, Don C Rockey
Sep 4, 2020·Journal of Pharmacy Practice·Justin P Reinert, Kevin Burnham
Dec 9, 2015·The American Journal of Gastroenterology·Sanath AllampatiJasmohan S Bajaj
Apr 4, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·German Soriano, Jasmohan S Bajaj
Jun 4, 2020·Continuum : Lifelong Learning in Neurology·Halina White
Nov 26, 2020·Arquivos De Gastroenterologia·Paulo André Bispo Machado JÚniorAlcindo Pissaia Junior
Feb 11, 2021·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Ángel Daniel Santana VargasJose Luis Perez Hernandez
Mar 27, 2021·Journal of Hepato-biliary-pancreatic Sciences·Khadija A M GlalTarek M Mostafa
Apr 16, 2021·Physiological Measurement·Tope OyeladeAli R Mani
Aug 4, 2021·Metabolic Brain Disease·Frederik Teicher KirkThomas Damgaard Sandahl
Sep 28, 2021·Annals of Hepatology·Marlone Cunha-SilvaDaniel F Mazo

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