PMID: 9170618Apr 1, 1997Paper

Usefulness of 99Tcm-tetrofosmin scintimammography in palpable breast tumours

Nuclear Medicine Communications
J F BatistaE Sánchez

Abstract

The aim of this exploratory study was to assess the potential of discriminating malignant from non-malignant lesions using 99Tcm-tetrofosmin scintimammography in the detection of palpable breast tumours. Nine patients with palpable masses were studied; seven had malignant lesions and two had non-malignant lesions. All diagnoses were established by fine-needle aspiration (FNA) biopsy cytology. Each patient received 925 MBq (25 mCi) 99Tcm-tetrosfosmin intravenously. Planar prone views were acquired in the right lateral, left lateral and anterior positions, and the axillary regions were included in the field of view. Scintimammography showed focally increased tracer uptake in seven patients with a positive FNA result. The two patients with a negative FNA result showed no increased uptake. We suggest that 99Tcm-tetrosfosmin shows promise as a radiopharmaceutical in the detection and discrimination of the nature of palpable breast tumours. Larger studies are required to confirm these findings.

Citations

Apr 1, 2000·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·V IvancevicD L Munz
Aug 2, 2003·Breast Cancer Research and Treatment·Moishe LibermanJohn S Sampalis
Jun 24, 2006·Nuclear Medicine Communications·Rahain Hussain, John R Buscombe
Feb 18, 2004·The Breast : Official Journal of the European Society of Mastology·P BerghammerH Sinzinger

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