Usefulness of a saline chaser to reduce contrast material dose in abdominal CT of normal dogs

Journal of Veterinary Science
Hyejin KimMincheol Choi

Abstract

Use of a saline chaser has been reported to allow reduction of contrast dose and artifacts during computed tomography (CT) examination in humans. This study assesses the extent of contrast dose by using a saline chaser in abdominal CT scans of normal dogs. Five beagles underwent abdominal CT scans. Three protocols were applied: 600 mg I/kg iohexol without saline chaser (protocol 1), 30% lower dose of iohexol (420 mg I/kg) followed by a 10 mL saline chaser (protocol 2), and 40% lower dose of iohexol (360 mg I/kg) followed by a 10 mL saline chaser (protocol 3). Attenuation values were obtained from aorta, portal vein, and liver parenchyma. The maximum enhancement values (MEVs) in protocol 2 were significantly higher than those in protocols 1 and 3 in the aorta; no difference was seen in the portal vein in all protocols. The liver parenchymal MEVs in protocols 1 and 2 were significantly higher than those obtained in protocol 3. In this study, the use of a saline chaser and a reduced dose of contrast material did not affect vessel enhancement. In conclusion, use of a saline chaser for abdominal CT of dogs is recommended because it allows a 30% reduction of contrast dose without decreasing vascular and hepatic parenchymal enhancement.

References

Mar 21, 2003·AJR. American Journal of Roentgenology·Paul J DorioSarah A Shock
Nov 6, 2003·Journal of Computer Assisted Tomography·Helmut SchoellnastMartin M Uggowitzer
Dec 23, 2003·European Radiology·Filippo CademartiriGabriel P Krestin
May 25, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Ilan Goldenberg, Shlomi Matetzky
Jul 25, 2006·AJR. American Journal of Roentgenology·Florence OrlandiniAlain Blum

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