PMID: 2119299Sep 1, 1990Paper

Usefulness of an aura for classification of a first generalized seizure

Epilepsia
C A van DonselaarR J Schimsheimer

Abstract

In 67 of 149 patients with a generalized first seizure, the occurrence of some kind of sensation immediately preceding the loss of consciousness was the only clue that possibly indicated focal onset of the seizure. We studied the interobserver agreement between six neurologists regarding the interpretation of these preceding feelings as either a nonspecific symptom or an aura implicating a focal onset of the seizure. The observers also classified the seizures as generalized from onset, undetermined, or partial secondarily generalized. To assess the accuracy of the classification, we obtained a standard EEG, an EEG after partial sleep deprivation, a computed tomography (CT) scan, and a follow-up report after 1 year. The subclassification on clinical grounds of a generalized first seizure is too unreliable and probably too invalid as well to be useful in clinical practice or in epidemiologic research.

References

Feb 1, 1989·Neurology·C A van DonselaarA Staal
Jan 1, 1986·Epilepsia·J F AnnegersL T Kurland
Jul 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·J W Sander, S D Shorvon
Oct 1, 1987·Archives of Neurology·W T LongstrethG van Belle
May 1, 1987·Epilepsia·E Rodin
Jun 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·D C Taylor, M Lochery
Sep 1, 1972·Archives of Neurology·L C JohnsonR D Walter
Aug 26, 1982·The New England Journal of Medicine·W A HauserS M McRoberts
Feb 1, 1963·Electroencephalography and Clinical Neurophysiology·J M VAN BUREN

❮ Previous
Next ❯

Citations

May 10, 2005·Epilepsy & Behavior : E&B·Betül BaykanUNKNOWN Epibase Group
Jul 15, 1998·Seizure : the Journal of the British Epilepsy Association·P RajnaE Wagner
Jul 15, 2009·Nature Reviews. Neurology·J Gert van DijkWouter Wieling
Jul 21, 1998·The New England Journal of Medicine·T W Meade
Nov 1, 1992·Epilepsia·D C ReutensS F Berkovic
Mar 16, 1991·BMJ : British Medical Journal·C A van DonselaarR J Schimsheimer
Aug 8, 2015·Epilepsy Currents·David Spencer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.