Usefulness of Bi-Parametric Magnetic Resonance Imaging with b=1,800 s/mm² Diffusion-Weighted Imaging for Diagnosing Clinically Significant Prostate Cancer

The World Journal of Men's Health
Seung Soo LeeSung Woo Park

Abstract

This study was conducted to compare the accuracy of bi-parametric magnetic resonance imaging (bpMRI) with high b-value (b=1,000 s/mm², b1000) diffusion-weighted imaging (DWI) to that of bpMRI with ultra-high b-value (b=1,800 s/mm², b1800) DWI to detect clinically significant prostate cancer (csPCa). A total of 408 patients with suspected PCa were evaluated by bpMRI prior to biopsy. One reader retrospectively reviewed all images for confirmation of Prostate Imaging-Reporting and Data System (PI-RADS) score. Cognitive magnetic resonance/ultrasound fusion target biopsy was done for all visible lesions (PI-RADS 3-5). Systematic biopsy was done for all cases. The csPCa detection rates were compared according to the bpMRI protocol (with/without b1800 DWI) or PI-RADS score. The accuracy of PI-RADS score was estimated using receiver operating characteristics curve. The signal intensity (SI) ratio (visible lesion/surrounding background) was evaluated. Among 164 men confirmed having PCa, 102 had csPCa (Gleason score≥7). Proportions of PI-RADS score 1-2/3/4/5 without b1800 DWI (n=133) and with b1800 DWI (n=275) were 19.5%/57.9%/15.8%/6.8% and 21.1%/48.7%/22.2%/8.0%, respectively. csPCa detection rates with/without b1800 DWI were 27.6%/19....Continue Reading

References

Jul 1, 2014·World Journal of Radiology·Leonardo K BittencourtDaniel Hausmann
Oct 3, 2015·European Urology·Jeffrey C WeinrebSadna Verma
Jul 8, 2016·Journal of Magnetic Resonance Imaging : JMRI·Harsh K AgarwalBaris Turkbey
Mar 20, 2018·The New England Journal of Medicine·Veeru KasivisvanathanUNKNOWN PRECISION Study Group Collaborators

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Methods Mentioned

BETA
biopsy

Software Mentioned

MedCalc
RADS
PI

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