Usefulness of brain natriuretic peptide levels to discriminate patients with stable angina pectoris without and with electrocardiographic myocardial ischemia and patients with healed myocardial infarction

The American Journal of Cardiology
Barbara PalumboRenato Palumbo

Abstract

Brain natriuretic peptide (BNP) levels were measured in 100 patients with coronary heart disease (CHD) who underwent myocardial stress thallium-201 single-photon emission computed tomography (30 with stable angina without basal electrocardiographic ischemia and no perfusion defects, 31 with angina with electrocardiographic ischemia and reversible perfusion defects, and 39 with myocardial infarction and irreversible defects) and in 42 controls. BNP levels progressively increased in patients with CHD and were significantly greater in patients with ischemia (p <0.01) and infarction (p <0.001) compared with controls and subjects with angina. BNP concentration was correlated positively (r = 0.923, p <0.001) with perfusion defect extent and inversely (r = -0.690, p <0.001) with the left ventricle ejection fraction (not different in the subjects examined).

Citations

Jun 11, 2005·Journal of Cardiac Failure·Kiang-Teck J YeoRobert S Foote
Nov 21, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gerald VanzettoJacques Machecourt
Feb 24, 2009·The American Journal of Cardiology·P Marc van der ZeeRobbert J de Winter
Dec 28, 2010·The American Journal of Cardiology·M Adnan NadirAllan D Struthers
Sep 28, 2005·International Journal of Cardiology·Takeshi YamamotoTeruo Takano

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