Abstract
This study was conducted to assess outcomes after percutaneous transluminal septal myocardial ablation (PTSMA) treatment in 131 patients (mean age 56+/-16 years) with obstructive hypertrophic cardiomyopathy. In-hospital and follow-up complications as well as late PTSMA failure (defined as unsatisfactory clinical outcome and a significant residual outflow tract gradient, necessitating reintervention) were noted. Baseline clinical, echocardiographic, and PTSMA characteristics were examined as determinants of outcomes. Also, the effect of ethanol volume and the role of a learning curve were investigated. PTSMA was successful in 90% of the patients. In-hospital and follow-up cardiac events were noted in 20 patients, including cardiac death (in-hospital n=4, follow-up n=1), acute myocardial infarction due to ethanol leakage (n=1), coronary dissection (n=2), nonfatal cardiac tamponade (n=1), and permanent pacemaker (n=6) or cardiac defibrillator (in-hospital n=4, follow-up n=1) implantation. Late PTSMA failure was noted in 12 patients. All baseline characteristics were comparable between successful and failed PTSMA. Ethanol volume was related to peak creatinine kinase value (p<0.0001) but not to late PTSMA failure or greater need for...Continue Reading
References
May 1, 1983·Circulation·P Spirito, B J Maron
Jul 22, 1995·Lancet·U Sigwart
Jul 21, 1998·Journal of the American College of Cardiology·S F NaguehW H Spencer
Oct 27, 1998·Circulation·N M LakkisW H Spencer
Dec 1, 1998·Circulation·L FaberU Gleichmann
Jun 11, 1999·The Thoracic and Cardiovascular Surgeon·H SeggewissU Gleichmann
Aug 27, 1999·European Heart Journal·F H GietzenH J Kuhn
Sep 15, 2000·Journal of the American College of Cardiology·N M LakkisW H Spencer
Jun 2, 2001·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·T M BashoreUNKNOWN American College of Cardiology/American Heart Association
Jun 20, 2001·Circulation·S C SmithUNKNOWN Society for Cardiac Angiography and Interventions
Aug 31, 2001·Journal of the American College of Cardiology·P BoekstegersG Steinbeck
Dec 9, 2003·American Heart Journal·Su min ChangNasser Lakkis
Jan 13, 2004·Journal of the American College of Cardiology·Willem G van DockumAlbert C van Rossum
Jan 24, 2004·Zeitschrift für Kardiologie·H KuhnL Seipel
Feb 18, 2004·Circulation·Su Min ChangSherif F Nagueh
Apr 15, 2004·The American Journal of Cardiology·Wibke ReinhardJeroen Vos
Sep 25, 2004·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Josef VeselkaTomás Honek
Dec 14, 2004·The American Journal of Cardiology·Daniel MonakierHarry Rakowski
Apr 14, 2005·Pacing and Clinical Electrophysiology : PACE·Thorsten LawrenzHorst Kuhn
Jul 20, 2005·Circulation·Chris van der LeePatrick W Serruys
Citations
May 9, 2014·Texas Heart Institute Journal·Jen-Te HsuKuo-Li Pan
Jul 25, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R C SteggerdaJ M Ten Berg
Dec 3, 2014·JACC. Heart Failure·Pieter A VriesendorpMichelle Michels
Nov 29, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Josef VeselkaHorst Kuhn
Jul 15, 2009·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Neeraj Parakh, Balram Bhargava
Mar 8, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Max LiebregtsJurriën M Ten Berg
Mar 12, 2016·JACC. Cardiovascular Interventions·Max LiebregtsJurriën M ten Berg
Oct 20, 2014·JACC. Cardiovascular Interventions·Robbert C SteggerdaMaarten P van den Berg
Jan 13, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Patrick AntounJeffrey A Breall
Nov 18, 2009·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Waleed BrinjikjiPhilip A Araoz
Jul 26, 2015·The American Journal of Cardiology·Mitsunobu KitamuraWataru Shimizu
Nov 15, 2011·Journal of the American College of Cardiology·Bernard J GershClyde W Yancy
Nov 15, 2011·Journal of the American College of Cardiology·Bernard J GershUNKNOWN American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Feb 2, 2015·The International Journal of Cardiovascular Imaging·Robbert C SteggerdaMaarten P van den Berg
Nov 19, 2011·The Journal of Thoracic and Cardiovascular Surgery·Bernard J GershClyde W Yancy
Nov 19, 2011·The Journal of Thoracic and Cardiovascular Surgery·Bernard J GershClyde W Yancy
Jul 31, 2014·Heart·Jippe C BaltJurriën M ten Berg
Mar 13, 2016·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Travis J MossJoseph L Schuller
Sep 9, 2017·Heart·Robert M Cooper, Rodney H Stables
Jun 19, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Yuichiro MaekawaShuichiro Takanashi
May 5, 2011·Circulation. Cardiovascular Interventions·Morten Kvistholm JensenHenning Bundgaard
Mar 4, 2010·Circulation. Cardiovascular Interventions·Robert A LeonardiAndrew Wang
Mar 25, 2010·Circulation. Heart Failure·Folkert J ten CatePatrick W Serruys
Nov 10, 2011·Circulation·Bernard J GershUNKNOWN Society of Thoracic Surgeons
Nov 10, 2011·Circulation·Bernard J GershUNKNOWN Society of Thoracic Surgeons
Dec 23, 2015·Echo Research and Practice·Robert M CooperRodney H Stables
Mar 26, 2014·Journal of Cardiovascular Medicine·Anna AxelssonMorten Kvistholm Jensen