Usefulness of clinical, echocardiographic, and procedural characteristics to predict outcome after percutaneous transluminal septal myocardial ablation

The American Journal of Cardiology
Chris van der LeeFolkert J ten Cate

Abstract

This study was conducted to assess outcomes after percutaneous transluminal septal myocardial ablation (PTSMA) treatment in 131 patients (mean age 56+/-16 years) with obstructive hypertrophic cardiomyopathy. In-hospital and follow-up complications as well as late PTSMA failure (defined as unsatisfactory clinical outcome and a significant residual outflow tract gradient, necessitating reintervention) were noted. Baseline clinical, echocardiographic, and PTSMA characteristics were examined as determinants of outcomes. Also, the effect of ethanol volume and the role of a learning curve were investigated. PTSMA was successful in 90% of the patients. In-hospital and follow-up cardiac events were noted in 20 patients, including cardiac death (in-hospital n=4, follow-up n=1), acute myocardial infarction due to ethanol leakage (n=1), coronary dissection (n=2), nonfatal cardiac tamponade (n=1), and permanent pacemaker (n=6) or cardiac defibrillator (in-hospital n=4, follow-up n=1) implantation. Late PTSMA failure was noted in 12 patients. All baseline characteristics were comparable between successful and failed PTSMA. Ethanol volume was related to peak creatinine kinase value (p<0.0001) but not to late PTSMA failure or greater need for...Continue Reading

References

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Citations

Jul 25, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·R C SteggerdaJ M Ten Berg
Dec 3, 2014·JACC. Heart Failure·Pieter A VriesendorpMichelle Michels
Nov 29, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Josef VeselkaHorst Kuhn
Jul 15, 2009·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Neeraj Parakh, Balram Bhargava
Mar 8, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Max LiebregtsJurriën M Ten Berg
Mar 12, 2016·JACC. Cardiovascular Interventions·Max LiebregtsJurriën M ten Berg
Jan 13, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Patrick AntounJeffrey A Breall
Nov 18, 2009·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Waleed BrinjikjiPhilip A Araoz
Mar 13, 2016·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Travis J MossJoseph L Schuller
Sep 9, 2017·Heart·Robert M Cooper, Rodney H Stables
Jun 19, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Yuichiro MaekawaShuichiro Takanashi
Mar 26, 2014·Journal of Cardiovascular Medicine·Anna AxelssonMorten Kvistholm Jensen

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