Usefulness of hypertriglyceridemia in predicting myocardial infarction late after coronary artery bypass operation

The American Journal of Cardiology
A A VoorsH W Plokker

Abstract

We prospectively followed 446 consecutive patients who had coronary bypass operations 15 years earlier. Serum levels of cholesterol and triglycerides were measured before and 5 years after bypass, and we established the relation between these lipid levels and the incidence of myocardial infarction (MI) and cardiac mortality during 15 years of follow-up. Follow-up was complete in 99.8% of the patients and averaged 15.4 years for the survivors. Multivariate Cox proportional-hazards analysis revealed that patients with preoperative hypertriglyceridemia (> or = 2.0 mmol/L [176 mg/dl]) had a 2.1 times increased risk for MI during follow-up (p = 0.04). Hypertriglyceridemic patients 5 years after surgery had a 2.2 times increased risk for MI during the subsequent follow-up period, although this difference was not statistically significant (p = 0.09). The only significant risk factor for MI 5 years after surgery was smoking. Hypercholesterolemia (> or = 6.5 mmol/L [254 mg/dl]) both before and 5 years after surgery was not a risk factor for MI during follow-up. Cardiac mortality was not significantly related to either hypercholesterolemia or hypertriglyceridemia. Independent predictors for cardiac mortality were poor left ventricular fu...Continue Reading

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Citations

Aug 3, 2000·The American Journal of Cardiology·D L SprecherF J Pashkow
Feb 14, 2015·Circulation·Alexander KulikUNKNOWN American Heart Association Council on Cardiovascular Surgery and Anesthesia
Feb 11, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M SolatiF Azizi
Oct 18, 2016·Current Opinion in Cardiology·Alexander Kulik
Aug 17, 2000·Current Opinion in Lipidology·P Alaupovic
Dec 6, 2019·Cardiology in Review·David Collins, Sheldon Goldberg

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