Usefulness of isovolumic and systolic ejection signals by tissue Doppler for the assessment of left ventricular systolic function in ischemic or idiopathic dilated cardiomyopathy

The American Journal of Cardiology
Qinyun Ruan, Sherif F Nagueh

Abstract

Echocardiography is the imaging modality most frequently used to assess left ventricular ejection fraction (EF). However, the accuracy of the EF can be limited by the technical quality of the examination and observer variability. Recently, tissue Doppler was applied to acquire signals of myocardial systolic function, including systolic ejection velocity (S(a)) and the systolic isovolumic acceleration rate (IVA). In that regard, IVA was reported in animal studies to be the ideal noninvasive index, because it was not affected by preload and afterload and provided a reliable assessment of contractility when examined against invasive gold standards. However, a paucity of data is available about its clinical application. We undertook this investigation to examine S(a) and IVA in 40 normal subjects and 52 patients with depressed EF referred for echocardiographic examination, aiming to identify the signal with the highest reproducibility and the most accurate detection of depressed EF. S(a) had the least inter- and intraobserver variabilities (3 +/- 1.5% and 2.5 +/- 1%, respectively), and IVA had the highest variability (8.1 +/- 2.1% and 6.8 +/- 2%, respectively). Although S(a) and IVA were significantly lower in patients with depress...Continue Reading

References

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Citations

Jan 15, 2011·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Suchi GroverJoseph B Selvanayagam
Apr 17, 2010·JACC. Cardiovascular Imaging·Darryl P LeongJoseph B Selvanayagam
Dec 26, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Laura ErnandeGeneviève Derumeaux
Dec 22, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Kai HuFrank Weidemann
Mar 6, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Andrei D MargulescuAlan G Fraser
Jul 5, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Thomas H MarwickJose L Zamorano
Dec 18, 2007·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Hiroyasu BitohAtsuhiro Sakamoto
Apr 26, 2014·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Haibin ZhangMiaozhang Zhu
Mar 3, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J E A K BamfoJ B Chambers

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