Usefulness of manufactured tomato extracts in the diagnosis of tomato sensitization: Comparison with the prick-prick method

Clinical and Molecular Allergy : CMA
Angel FerrerJ Carnés

Abstract

Commercial available skin prick test with fruits can be negative in sensitized or allergic patients due to a reduction in biological activity during the manufacturing process. Prick-prick tests with fresh foods are often preferred, but they are a non-standardized procedure. The usefulness of freeze-dried extracts of Canary Islands tomatoes, comparing the wheal sizes induced by prick test with the prick-prick method in the diagnosis of tomato sensitization has been analyzed.The objective of the study was to assess the potential diagnostic of freeze-dried extracts of Canary Islands tomatoes, comparing the wheal sizes induced by prick test with the prick-prick method. Two groups of patients were analyzed: Group I: 26 individuals reporting clinical symptoms induced by tomato contact or ingestion. Group II: 71 control individuals with no symptoms induced by tomato: 12 of them were previously skin prick test positive to a tomato extract, 39 were atopic and 20 were non-atopic. All individuals underwent prick-prick with fresh ripe peel Canary tomatoes and skin prick tested with freeze-dried peel and pulp extracts obtained from peel and pulp of Canary tomatoes at 10 mg/ml. Wheal sizes and prick test positivity (>/= 7 mm2) were compared ...Continue Reading

References

Sep 2, 1998·The Journal of Allergy and Clinical Immunology·J Cuesta-HerranzM de-Las-Heras
Apr 9, 1999·Allergy·R AseroP Falagiani
Jul 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R AseroP Falagiani
Oct 3, 2002·Allergy·J CarnésJ Cuesta-Herranz
Apr 25, 2003·Medical Hypotheses·Carlos H Larramendi
Nov 30, 2005·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Angel FerrerEnrique Fernández-Caldas
Dec 30, 2006·Molecular Nutrition & Food Research·Riccardo AseroStefan Vieths
Nov 17, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C H LarramendiJ Carnés

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Citations

Dec 2, 2009·Current Opinion in Allergy and Clinical Immunology·Efimia Papadopoulou-Alataki

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Software Mentioned

PC Draft
SigmaPlot
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