Usefulness of positron emission tomography/computed tomography in patients with valve-tube graft infection

Heart
Daniel García-ArribasJosé Luis Carreras

Abstract

Infection of valved aortic grafts is a rare entity whose diagnosis remains challenging. Positron emission tomography (PET)/CT has become a criterion for the diagnosis of infective endocarditis (IE) in prosthetic valves, but its role on ascending aortic graft infections remains unclear. This study aims to assess the diagnostic value of PET/CT in patients with valved aortic graft infection. 12 episodes with a valved aortic graft who had undergone a PET/CT due to suspicion of IE were prospectively included (group I) and compared with five controls free of infection who underwent PET/CT for other reasons (group II). Pathological uptake of 18F-fluorodeoxyglucose (FDG) and its pattern at the prosthetic valve and aortic graft were studied. Diagnosis of IE was confirmed in 9 out of 12 episodes of group I. 18F-FDG uptake was detectable in eight out of nine cases with a final diagnosis of IE. The most repeated pattern of uptake was homogeneous around the valve and heterogeneous around the tube. There was one false-negative study. Of the three patients in which IE was ruled out, there were two false positives and one true negative. In group II, there were three patients with a positive PET/CT study, two of them had active aortitis and the...Continue Reading

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Citations

May 23, 2019·Heart·Carlos Nicolás Pérez-GarcíaIsidre Vilacosta
Jun 9, 2019·Nature Reviews. Cardiology·Bernard Iung, Xavier Duval
Feb 5, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Daniel Martínez-LópezAlberto Forteza Gil
Feb 17, 2021·International Journal of Cardiology·Daniel García-ArribasLuis Maroto
Apr 2, 2021·International Journal of Cardiology·Bo Xu, Reza Reyaldeen
Apr 2, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Ayako IshikitaHiroyuki Tsutsui

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