Usefulness of Serum Albumin Concentration to Predict High Coronary SYNTAX Score and In-Hospital Mortality in Patients With Acute Coronary Syndrome

Angiology
Alparslan KurtulOzlem Aksoy

Abstract

High SYNTAX score is a predictor of adverse cardiovascular events, including mortality, in acute coronary syndromes (ACSs). Decreased serum albumin (SA) concentration is associated with an increased risk of cardiovascular events. We aimed to investigate whether SA levels at admission are associated with high SYNTAX score and in-hospital mortality in patients with ACS. The study included 1303 patients with ACS who underwent coronary angiography (CA). The patients were divided into 2 groups as high SYNTAX score (≥33) and lower SYNTAX score (≤32). Baseline SA levels were significantly lower in patients with high SYNTAX score than with lower SYNTAX score (3.46 ± 0.42 mg/dL vs 3.97±0.37 mg/dL, respectively; P < .001). On multivariate logistic regression, SA (<3.65 mg/dL) was an independent predictor of high SYNTAX score (odds ratio 4.329, 95% confidence interval 2.028-8.264; P < .001) together with admission glucose, estimated glomerular filtration rate, and left ventricular ejection fraction. In Cox regression analyses, systolic blood pressure, high SYNTAX score, and SA (<3.65 mg/dL) were found as independent predictors of in-hospital all-cause mortality. In conclusion, SA concentration on admission is inversely associated with hig...Continue Reading

References

Aug 19, 1976·The New England Journal of Medicine·R Ross, J A Glomset
Jan 1, 1985·Advances in Protein Chemistry·T Peters
Jan 22, 2005·Seminars in Dialysis·Burl R Don, George Kaysen
Apr 16, 2008·Journal of Internal Medicine·T ThimE Falk
Apr 29, 2008·American Heart Journal·Tamara B HorwichGregg C Fonarow
May 14, 2008·FEBS Letters·Marjolaine RocheEmmanuel Bourdon
Aug 19, 2010·International Heart Journal·Anggoro Budi HartopoBudi Yuli Setianto
Jan 1, 1996·Platelets·D P Mikhailidis, E S Ganotakis
Sep 21, 2013·Kardiologia polska·Berkay EkiciHasan Fehmi Töre
Jan 11, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mayank YadavGregg W Stone
Mar 20, 2014·Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır·Aslı TanındıHasan Fehmi Töre

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Citations

Sep 22, 2011·International Journal of Surgery·Ajaz Ahmad MalikNayeem Ul-Hassan
Apr 19, 2018·Journal of Clinical Laboratory Analysis·Yavuz KarabağIbrahim Halil Tanboğa
Nov 21, 2017·Biomarker Research·Shih-Chieh ChienHung-I Yeh
Mar 6, 2019·Scandinavian Cardiovascular Journal : SCJ·Tufan ÇınarHalil İbrahim Tanboğa
Oct 8, 2019·Therapeutic Advances in Cardiovascular Disease·Hakan DumanElif Ergül
Jan 7, 2020·Clinical and Experimental Nephrology·Yusuke UemuraUNKNOWN N-registry investigators
Dec 18, 2020·Arquivos brasileiros de cardiologia·Alper SercelikSerdar Turkmen
Mar 9, 2021·Angiology·Cagri Yayla, Kadriye Gayretli Yayla
Apr 4, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Xiaohan WangYisheng Xu

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS

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