Usefulness of subcutaneous nitrate for radial access

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Anissa OuadhourPatrick Henry

Abstract

We made the hypothesis that adjunction of nitrate to lidocaine for local anesthesia may facilitate accessibility of radial access. Transradial approach is associated with a clear decrease in the rate of access bleeding when compared with femoral approach. The diffusion of this technique remains limited due to the small size and the spastic profile of this artery. Eighty-four consecutive patients undergoing coronary procedures using radial approach were randomly assigned between two types of local anesthesia (double blind): 5 ml lidocaine (group L)-5 ml lidocaine + 0.5 mg dinitrate isosorbide (group LN). The primary endpoint was the duration of radial puncture (from beginning of local anesthesia to sheath insertion) and the total number of punctures. Sixty-two men and 22 women (mean age 59 +/- 8 y.o.) were included. Mean +/- SEM access duration was 3:33 +/- 3:11 min in group L when compared with 2:26 +/- 1:20 min in group LN (P < 0.05). Mean number of puncture was 1.50 +/- 1.0 in group L when compared with 1.16 +/- 0.5 in group LN (P = 0.05). There were no differences between two groups concerning pain score during anesthesia and sheath insertion. There was no difference between two groups concerning the rate of hypotensive and ...Continue Reading

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Citations

Jun 14, 2015·Indian Heart Journal·Santhosh Satheesh, Anandaraja Subramanian
Jan 10, 2012·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Hee Hwa HoPaul Jau Ong
Mar 21, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Francesco BurzottaFilippo Crea
May 14, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Yumiko KaneiShigeru Saito
Sep 21, 2015·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Burak Turanİsmail Erden
Oct 1, 2017·Journal of Neurointerventional Surgery·Brian M SnellingEric C Peterson
Feb 4, 2016·Circulation. Cardiovascular Interventions·Francesco CostaNicolas M Van Mieghem
Jun 2, 2012·Expert Review of Cardiovascular Therapy·Tariq BhatBhavesh Gala
Jun 25, 2019·Coronary Artery Disease·Jerzy WojciukAndrew Wiper
Sep 10, 2020·Surgical Neurology International·Luis Alberto Domitrovic ZalocarJavier Goland

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