Usefulness of the forced oscillation technique in assessing the therapeutic result of tracheobronchial central airway obstruction

Respiratory Investigation
Masanori YasuoMasayuki Hanaoka

Abstract

Pulmonary function tests (PFTs) comprise the traditional method for detecting central airway obstruction (CAO) and evaluating therapeutic effects, but are effort-dependent. By contrast, the forced oscillation technique (FOT) is performed during tidal breathing in an effort-independent mode and is universally used to assess respiratory function in patients with chronic obstructive pulmonary disease (COPD) and asthma. We used the FOT to measure airway resistance and reactance in patients with CAO before and after interventional bronchoscopy and compared the results to data obtained using PFTs. Twelve patients with CAO were recruited from December 2013 to July 2016. The FOT, PFTs, chest computed tomography (CT), COPD Assessment Test (CAT), and the modified Medical Research Council (mMRC) dyspnea scale were employed before and after interventional bronchoscopy. The minimum airway cross-sectional area (MACSA) was calculated using a CT image calculator. Of the 12 patients, 6 had tracheal obstruction and 6 had bronchial obstruction. All FOT measurements, except ΔX5, were significantly improved after interventional bronchoscopy in all cases. The significance of the improvement was greater with the FOT than PFTs. The MACSA, CAT, and mMR...Continue Reading

Citations

Jul 2, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Masanori YasuoMasayuki Hanaoka
Dec 5, 2020·Therapeutics and Clinical Risk Management·Noemi Porojan-SuppiniCristian Oancea

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