Usefulness of white-light imaging-guided narrow-band imaging for the differential diagnosis of small ampullary lesions

Gastrointestinal Endoscopy
Jin-Seok ParkMyung-Hwan Kim

Abstract

Small ampullary tumors and inflammatory lesions have similar endoscopic findings and are difficult to differentiate. Narrow-band imaging (NBI) can visualize microvessels and mucosal microstructure clearly and is widely used to diagnose early gastric and colon cancer. To evaluate the usefulness of NBI for differentiating ampullary tumors from benign diseases. Retrospective cohort study. Tertiary-care hospital. All 45 patients who had suspicious ampullary lesions (enlarged or protruded morphology) during duodenoscopy and underwent NBI between March 2010 and January 2011. NBI. NBI images were assessed for irregular villous arrangement, irregular villous size, ridge disappearance, demarcation with normal villi, and abnormal microvasculature. Histology of NBI-guided lesion biopsy specimens provided the final diagnoses. Agreement between NBI images and histologic findings was analyzed. Of the 60 ampullary lesions, 11, 26, and 23 were adenocarcinomas, adenomas, and benign inflammatory diseases, respectively. Irregular villous arrangement, irregular villous size, ridge disappearance, demarcation with normal villi, and abnormal microvasculature were observed in 45%, 63%, 50%, 48%, and 58% of the lesions, respectively. Multivariate analy...Continue Reading

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Citations

Dec 15, 2020·Surgical Oncology·Francesca Boscolo NataNicolò de Manzini

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