Uses of plasma in Spain

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
M Algora, L Barbolla

Abstract

In Spain, fresh frozen plasma (FFP) currently recovered either by whole blood centrifugation or by apheresis is mainly considered as a source of plasma derivates rather than a product to be transfused. Upon this consideration, the amount of plasma transfused in the last two decades has remained stable, while the production of FFP has grown steadily during all these years. Thus, much more plasma has been derived to industry for manufacturing. Although, since 1993 a consensus conference established the clinical situation where plasma has demonstrated its efficacy, the true situation is that many indications seem not to be supported on a scientific evidence basis. Only a few studies have been performed in the last years to assess the appropriateness of these indications. We present the initial result of an ongoing survey addressed by the Madrid Blood Transfusion Centre. Based on the criteria of total amount of RBC transfused per year, large hospitals (more than 10,000 units of RBC) transfused an average of 23.87% of FFP, while medium hospitals (5000-10,000 units of RBC) used 19.5% and small ones (less than 5000) about 12.5%. It is important to point out that inside each group there were some important differences in ratio values f...Continue Reading

References

Jan 25, 1985·JAMA : the Journal of the American Medical Association
Jun 17, 2004·British Journal of Haematology·S J StanworthM F Murphy
Sep 1, 2005·Transfusion·Jodi B SegalUNKNOWN Transfusion Medicine/Hemostasis Clinical Trials Network

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Citations

Jun 3, 2009·Critical Care : the Official Journal of the Critical Care Forum·Bernard Vigué
Oct 1, 2013·Transfusion Medicine Reviews·Miguel LozanoThomas H Müller

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