Abstract
Imaging phantoms are widely used for testing and optimization of imaging devices without the need to expose humans to irradiation. However, commercially available phantoms are commonly manufactured in simple, generic forms and sizes and therefore do not resemble the clinical situation for many patients. Using 3D printing techniques, we created a life-size phantom based on a clinical CT scan of the thorax from a patient with lung cancer. It was assembled from bony structures printed in gypsum, lung structures consisting of airways, blood vessels >1 mm, and outer lung surface, three lung tumors printed in nylon, and soft tissues represented by silicone (poured into a 3D-printed mold). Kilovoltage x-ray and CT images of the phantom closely resemble those of the real patient in terms of size, shapes, and structures. Surface comparison using 3D models obtained from the phantom and the 3D models used for printing showed mean differences <1 mm for all structures. Tensile tests of the materials used for the phantom show that the phantom is able to endure radiation doses over 24,000 Gy. It is feasible to create an anthropomorphic thorax phantom using 3D printing and molding techniques. The phantom closely resembles a real patient in ter...Continue Reading
References
Nov 1, 1978·Medical Physics·D R White
Jan 18, 2011·Medical Engineering & Physics·Richard BibbJohn Winder
May 3, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Erin J SmithRandy E Ellis
Aug 21, 2013·International Journal of Radiation Oncology, Biology, Physics·Houda BahigEdith Filion
Sep 11, 2014·Physics in Medicine and Biology·Eric D EhlerKathryn E Dusenbery
Jan 8, 2015·Medical Physics·Rakesh PatelJohn C Roeske
Jan 22, 2015·Advances in Skin & Wound Care·Jessica L SparksTeresa A Conner-Kerr
Apr 4, 2015·Medical Physics·John R van Sörnsen de KosteWilko F A R Verbakel
May 6, 2015·International Journal of Radiation Oncology, Biology, Physics·Jinhong JungByungchul Cho
Jun 10, 2015·Physics in Medicine and Biology·D WallaceJ T Booth
Aug 4, 2015·The Review of Scientific Instruments·Rulon MayerCharles B Simone
Oct 3, 2015·Medical Physics·Matthew F BieniosekCraig S Levin
Oct 29, 2015·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Joseph MadamesilaRao Khan
Nov 13, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Dimitris MitsourasFrank J Rybicki
Feb 4, 2016·PloS One·Ian S KinstlingerJordan S Miller
Feb 5, 2016·Medical Physics·Nina I NiebuhrSteffen Greilich
Mar 16, 2016·Biomedical Optics Express·Gennifer T SmithAudrey K Ellerbee Bowden
Mar 31, 2016·International Journal of Radiation Oncology, Biology, Physics·Paul J KeallJeremy T Booth
Mar 31, 2016·International Journal of Radiation Oncology, Biology, Physics·Colien HazelaarWilko F A R Verbakel
Oct 9, 2016·International Journal of Computer Assisted Radiology and Surgery·Maureen van EijnattenJan Wolff
May 24, 2017·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Colien HazelaarWilko F A R Verbakel
Jul 15, 2017·Journal of Computer Assisted Tomography·Ramin Javan, Alexander L Cho
Mar 1, 2014·3D Printing and Additive Manufacturing·Aidan J CloonanTim M McGloughlin
Citations
May 2, 2018·Physics in Medicine and Biology·Colien HazelaarWilko Verbakel
Jul 10, 2018·Journal of Applied Clinical Medical Physics·Tyler MeyerMichael Roumeliotis
Jun 23, 2018·Medical Physics·Valeria Filippou, Charalampos Tsoumpas
Aug 26, 2018·Medical Physics·Nikiforos Okkalidis
Oct 27, 2018·Medical Physics·Pengpeng ZhangGig Mageras
Feb 19, 2019·Medical Physics·Lukasz J Nowak, Ewa Pawlowska
Jun 22, 2019·Physics in Medicine and Biology·Jenny BertholetUwe Oelfke
Sep 29, 2019·Physics in Medicine and Biology·R TinoT Kron
Dec 22, 2019·Medical Physics·Dong-Seok ShinTokihiro Yamamoto
Jan 4, 2020·Medical Physics·Chuang WangPengpeng Zhang
Feb 12, 2020·Physics in Medicine and Biology·Emma ColvillGiovanni Fattori
Aug 18, 2018·European Radiology·Paul JahnkeMichael Scheel
Sep 14, 2019·Technology in Cancer Research & Treatment·Rance TinoTomas Kron
Mar 12, 2020·Medical Physics·Robin B HolmesUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Feb 19, 2020·Medical Physics·Nikiforos Okkalidis, George Marinakis
Jun 20, 2020·Journal of Digital Imaging·Michael O'ReillyNathan M Cross
Jun 12, 2020·Physical and Engineering Sciences in Medicine·T KairnS B Crowe
May 28, 2020·Frontiers in Bioengineering and Biotechnology·Sepideh HatamikiaWolfgang Birkfellner
Sep 25, 2020·Medical Physics·Michel C ÖllersFrank Verhaegen
Dec 18, 2020·Ultrasound in Medicine & Biology·Lidia Al-ZogbiAxel Krieger
Jan 19, 2021·Biomedical Physics & Engineering Express·Tess ReynoldsRicky O'Brien
Mar 19, 2021·Medical Physics·Prashanth RaviFrank J Rybicki
May 6, 2021·Journal of Applied Clinical Medical Physics·H Henry GuoJia Wang
Jun 17, 2021·Dento Maxillo Facial Radiology·Sawyer Rhae BadiukDaniel W Rickey
Jul 3, 2021·Journal of Personalized Medicine·Jungirl SeokYuh-Seog Jung
Jul 10, 2021·Advanced Science·Zhongboyu JinYong He
Jun 12, 2021·Advances in Radiation Oncology·Kimmie de BruinWilko F A R Verbakel
Nov 20, 2021·Medical Physics·Rance Bolislis TinoTomas Kron
Dec 16, 2021·Medical Physics·Samantha Green, Jared Grice
Dec 16, 2021·Medical Physics·Kai MeiPeter B Noël
Dec 17, 2021·Medical Physics·Marco MuellerPaul Keall