Using a contrast-enhanced imaging sequence at 3-minute delay in 3-T magnetic resonance imaging for acute infarct evaluation

Investigative Radiology
Alexandre ComteHatem Boulahdour

Abstract

To investigate the performance of a delayed-enhancement (DE) sequence adapted for a 3-minute delay after bolus injection of a contrast media in cardiac magnetic resonance imaging (MRI) in acute reperfused myocardial infarction. Sixty-three patients with recent myocardial infarction underwent contrast-enhanced MRI. Sequences of first-pass (FP) perfusion imaging and DE imaging at 3 and 15 minutes were performed at the acute phase. Of these patients, 49 had a follow-up cardiac magnetic resonance examination. Infarct sizes were quantified by 2 experienced users with a 17-segment model at the acute phase (at FP and at 3- and 15-minute delay) and at the chronic phase (at 15 minutes because only fibrous areas hyperenhance late). Areas of hypoenhancement and hyperenhancement were also calculated. Results from the 3-minute imaging sequence at the acute phase were compared with the FP (taking into account dark signal areas), with the 15-minute DE imaging sequence results at the acute phase [taking into account dark signal and hyperenhanced (white plus dark signal) areas] and with the 15-minute DE imaging sequence from the chronic phase (taking into account hyperenhanced areas). Least squares regression and Bland-Altman plots were perform...Continue Reading

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Citations

Apr 13, 2010·Investigative Radiology·Val M Runge
Nov 13, 2008·Investigative Radiology·Val M Runge

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