Using a logistic model to identify women with first-trimester spontaneous abortion suitable for expectant management

British Journal of Obstetrics and Gynaecology
S NielsenA Odén

Abstract

To design a method to identify women with first trimester spontaneous abortion suitable for expectant management. A stepwise logistic regression analysis based on retrospective analysis of clinical and biochemical variables. Department of Obstetrics and Gynaecology, Sahlgrenska University Hospital, Gothenburg, Sweden. One hundred and three women with inevitable or incomplete spontaneous abortion at < 13 weeks of gestation were chosen for expectant management. Eighty-one women with complete spontaneous abortion (i.e. complete expulsion and/or resolution of pregnancy products within three days of expectant management) were compared with those (n = 22) who underwent surgical evacuation of the uterus, most commonly owing to retained products of conception after three days. Employing a stepwise logistic regression procedure, five diagnostic variables possessing prognostic power were identified: serum progesterone, daily serum hCG change, serum CA125, serum alpha fetoprotein and intrauterine diameter. The logistic regression analysis was also applied to three diagnostic variables chosen for routine clinical use: serum progesterone, serum hCG and intrauterine diameter. The probability of complete spontaneous abortion within three days...Continue Reading

References

Sep 1, 1992·Archives of Emergency Medicine·M McKeeN Black
Mar 23, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·M M Mansur
Dec 1, 1982·Annals of Emergency Medicine·R G FarrellR A Ridgeway
May 1, 1995·Human Reproduction·M HahlinI Bryman
Jan 14, 1995·Lancet·S Nielsen, M Hahlin

❮ Previous
Next ❯

Citations

Oct 31, 2002·Journal of Clinical Ultrasound : JCU·Ganesh Acharya, Heulwen Morgan
Sep 27, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·S A Thwaini Al Inizi, M Ezimokhai
Oct 18, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S Zalányi
Jun 26, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S SairamB Thilaganathan
Jun 6, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G Acharya, H Morgan
Oct 14, 2009·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M M El-SayedM H Jones
Apr 28, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M ShankarR A Kadir
Mar 24, 2009·Best Practice & Research. Clinical Obstetrics & Gynaecology·Shyamaly D Sur, Nicholas J Raine-Fenning
Aug 24, 1999·British Journal of Obstetrics and Gynaecology·S NielsenJ Platz-Christensen
Oct 8, 1998·British Journal of Obstetrics and Gynaecology·S Zalányi
Jul 3, 2004·Current Opinion in Obstetrics & Gynecology·Janine Elson, Davor Jurkovic
Apr 6, 2002·Hospital Medicine·Judith MooreJames J Walker
Apr 13, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A AgostiniB Blanc
Feb 17, 2007·Clinical Obstetrics and Gynecology·Maya Chetty, Janine Elson
Jun 1, 1997·British Journal of Obstetrics and Gynaecology·D G TincelloD G Wilkinson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.