Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction

European Heart Journal. Quality of Care & Clinical Outcomes
Eleni RapsomanikiHarry Hemingway

Abstract

To assess the international validity of using hospital record data to compare long-term outcomes in heart attack survivors. We used samples of national, ongoing, unselected record sources to assess three outcomes: cause death; a composite of myocardial infarction (MI), stroke, and all-cause death; and hospitalized bleeding. Patients aged 65 years and older entered the study 1 year following the most recent discharge for acute MI in 2002-11 [n = 54 841 (Sweden), 53 909 (USA), 4653 (England), and 961 (France)]. Across each of the four countries, we found consistent associations with 12 baseline prognostic factors and each of the three outcomes. In each country, we observed high 3-year crude cumulative risks of all-cause death (from 19.6% [England] to 30.2% [USA]); the composite of MI, stroke, or death [from 26.0% (France) to 36.2% (USA)]; and hospitalized bleeding [from 3.1% (France) to 5.3% (USA)]. After adjustments for baseline risk factors, risks were similar across all countries [relative risks (RRs) compared with Sweden not statistically significant], but higher in the USA for all-cause death [RR USA vs. Sweden, 1.14 (95% confidence interval 1.04-1.26)] and hospitalized bleeding [RR USA vs. Sweden, 1.54 (1.21-1.96)]. The val...Continue Reading

References

Mar 9, 2004·Health Affairs·Joseph P Newhouse
Jul 13, 2007·The New England Journal of Medicine·J Michael McWilliamsJohn Z Ayanian
Dec 27, 2007·JAMA : the Journal of the American Medical Association·J Michael McWilliamsJohn Z Ayanian
Aug 30, 2008·The American Journal of Cardiology·Benjamin A SteinbergUNKNOWN National Registry of Myocardial Infarction Investigators
Jan 19, 2010·British Journal of Clinical Pharmacology·Emily HerrettAndrew J Hall
Jan 29, 2010·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Laura-Mae BaldwinL Gary Hart
Jul 6, 2010·Revue D'épidémiologie Et De Santé Publique·P TuppinY Merlière
Jul 17, 2010·Journal of the American College of Cardiology·Matthew T RoeJohn S Rumsfeld
Sep 2, 2010·JAMA : the Journal of the American Medical Association·Deepak L BhattUNKNOWN REACH Registry Investigators
Dec 29, 2010·The American Journal of Medicine·David D McManusRobert J Goldberg
Aug 28, 2012·European Heart Journal·UNKNOWN Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)Doron Zahger
Dec 12, 2012·International Journal of Epidemiology·Spiros C DenaxasHarry Hemingway
Feb 7, 2013·BMJ : British Medical Journal·Harry HemingwayUNKNOWN PROGRESS Group
Oct 10, 2013·British Journal of Clinical Pharmacology·Mai DuongNicholas Moore
Jun 5, 2014·The New England Journal of Medicine·Sebastian Schneeweiss
Aug 12, 2014·JAMA Internal Medicine·Philippe Gabriel StegUNKNOWN Prospective Observational Longitudinal Registry of Patients With Stable Coronary Artery Disease (CLARIFY) Investigators
Dec 4, 2014·The Lancet. Diabetes & Endocrinology·Anoop Dinesh ShahHarry Hemingway
Dec 31, 2014·La Revue de médecine interne·G MoulisL Sailler
Mar 17, 2015·The New England Journal of Medicine·Marc P BonacaUNKNOWN PEGASUS-TIMI 54 Steering Committee and Investigators
Jun 8, 2015·International Journal of Epidemiology·Emily HerrettLiam Smeeth
Oct 24, 2015·British Journal of Clinical Pharmacology·Patrick BlinNicholas Moore
Jul 1, 2015·European Heart Journal. Quality of Care & Clinical Outcomes·Spiros C Denaxas, Katherine I Morley
Nov 1, 2015·European Heart Journal. Quality of Care & Clinical Outcomes·Karam Sadoon AlzuhairiChristian Torp-Pedersen

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Citations

Jan 26, 2018·European Heart Journal·Harry HemingwayUNKNOWN Innovative Medicines Initiative 2nd programme, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and ind
Nov 28, 2017·European Heart Journal. Quality of Care & Clinical Outcomes·Adam TimmisPanos Vardas
Jul 23, 2019·Journal of the American Medical Informatics Association : JAMIA·Spiros DenaxasHarry Hemingway
Jul 28, 2019·Cardiovascular Research·O A AlabasC P Gale
Aug 18, 2020·Cardiology and Therapy·Raghav SharmaYogesh Belagali
Mar 1, 2019·Internal Medicine Journal·Walter W C ChenTony C K Au Yeong
Dec 24, 2019·Expert Opinion on Investigational Drugs·Amit RoutPaul A Gurbel
Nov 26, 2016·Cardiovascular Therapeutics·Alfredo BardajíHéctor Bueno
May 26, 2017·Pharmacoepidemiology and Drug Safety·Julien BezinNicholas Moore
Aug 22, 2020·Journal of Lipid and Atherosclerosis·Kyu Kim, Sang-Hak Lee
Jul 11, 2018·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Jeffrey S Berger
Jul 31, 2019·Nature Reviews. Cardiology·Keith A A FoxDan Atar
Sep 10, 2020·Frontiers in Cardiovascular Medicine·Jianhua YaoJiahong Xu
Jul 1, 2016·European Heart Journal. Quality of Care & Clinical Outcomes·Edina CenkoRaffaele Bugiardini
Nov 27, 2020·European Heart Journal Supplements : Journal of the European Society of Cardiology·Leonardo Bolognese, Massimo Felici
Sep 26, 2020·ACS Biomaterials Science & Engineering·LaTonya R Simon, Kristyn S Masters
Dec 14, 2021·Frontiers in Cardiovascular Medicine·Ji Woong RohUNKNOWN KAMIR-NIH Investigators

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

CALIBER

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