Using contrast-enhanced sonography to assess the effectiveness of transcatheter arterial embolization for hepatocellular carcinoma

AJR. American Journal of Roentgenology
Kazushi NumataT Kubota

Abstract

We evaluated the usefulness of contrast-enhanced wideband harmonic gray-scale sonography in assessing the therapeutic effects of transcatheter arterial embolization for patients with hepatocellular carcinoma and compared the findings of this imaging modality with those of helical CT. Twenty-nine patients with 39 hepatocellular carcinoma lesions were examined. We scanned lesions before and after therapy using contrast-enhanced wideband harmonic gray-scale sonography after injection of a galactose-palmitic acid contrast agent. All patients held their breath for 20--50 sec after injection while the vascularity of the tumor was observed. We then monitored tumor enhancement between 60 and 180 sec after injection with patients breath-holding for a few seconds. Lesions were considered to exhibit viable tumor residue if hypervascular enhancement was observed in the tumor. We compared this enhancement with helical CT findings. After therapy, 36 of the 39 lesions showed viable tumor residue on contrast-enhanced wideband harmonic gray-scale sonography, with no artifacts from iodized oil. Helical CT revealed a high-attenuation area in 12 of the 36 lesions, whereas 24 of the 36 lesions could not be evaluated for tumor residue as a result of...Continue Reading

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Citations

Oct 13, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·H RhimO K Cho
Dec 20, 2002·AJR. American Journal of Roentgenology·Kazushi NumataKatsuaki Tanaka
Feb 20, 2003·AJR. American Journal of Roentgenology·Yasunori MinamiHitoshi Shiozaki
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Dec 17, 2010·World Journal of Radiology·Kazushi NumataKatsuaki Tanaka
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Jul 30, 2011·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Fangyi LiuBaowei Dong
Aug 23, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yukinobu WatanabeMitsuhiko Moriyama
Sep 27, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ji Hyun YoukChong Soo Kim
Oct 31, 2006·World Journal of Gastroenterology : WJG·Kazushi NumataKatsuaki Tanaka
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Sep 27, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hitoshi MaruyamaKeiji Miyata

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