PMID: 11308883Apr 20, 2001Paper

Using DNA to construct and power a nanoactuator

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Friedrich C Simmel, Bernard Yurke

Abstract

A DNA-based molecular machine is described which has two movable arms that are pushed apart when a strand of DNA, the fuel strand, hybridizes with a single-stranded region of the molecular machine. Through the process of branch migration, a second strand of DNA complementary to the fuel strand is able to remove the fuel strand from the molecular machine, restoring it to its original configuration. Compared with the molecular tweezers we had previously devised, this machine, which we call a nanoactuator, has a reduced tendency to form dimers.

References

Apr 24, 1981·Nucleic Acids Research·C Green, C Tibbetts
Mar 19, 1996·Biochemistry·J SantaLuciaP A Seneviratne
Aug 15, 1996·Nature·A P AlivisatosP G Schultz
Mar 13, 1997·Nature·C MaoN C Seeman
May 1, 1997·Nature Biotechnology·R R Breaker
Mar 25, 1998·Biophysical Journal·H Y WangG Oster
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·G F Joyce
Aug 26, 1998·Nature·E WinfreeN C Seeman
Sep 6, 1993·Physical Review Letters·M O Magnasco
Mar 14, 1994·Physical Review Letters·R D Astumian, M Bier
Feb 27, 1995·Physical Review Letters·L P FaucheuxA J Libchaber
Sep 25, 1995·Physical Review Letters·F Jülicher, J Prost
Sep 18, 1999·Nature·T R KellyR A Silva
Sep 18, 1999·Nature·N KoumuraB L Feringa
Feb 7, 2001·Science·L Mahadevan, P Matsudaira
Aug 19, 2000·Nature·B YurkeJ L Neumann
Sep 16, 2000·Physical Review Letters·A W Ghosh, S V Khare
Sep 16, 2000·Physical Review Letters·M PortoJ Klafter
Sep 16, 2000·Physical Review Letters·M PortoJ Klafter

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Citations

Jan 25, 2011·Nature Chemistry·David Yu Zhang, Georg Seelig
Dec 18, 2004·Science·Shiping Liao, Nadrian C Seeman
Mar 27, 2010·Advanced Drug Delivery Reviews·Michael J CampolongoDan Luo
Sep 9, 2015·Chemical Reviews·Sundus Erbas-CakmakAlina L Nussbaumer
Jul 17, 2004·Annual Review of Biomedical Engineering·C MavroidisM L Yarmush
Mar 9, 2005·Trends in Biochemical Sciences·Nadrian C Seeman
Feb 2, 2018·Advanced Materials·Yuezhou ZhangHongbo Zhang
Mar 25, 2011·Angewandte Chemie·Yamuna Krishnan, Friedrich C Simmel
Oct 3, 2018·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Yao-Sheng Li, Xue-Feng Wang
Feb 11, 2005·Organic & Biomolecular Chemistry·Marco BrucaleBruno Samorì
Nov 30, 2006·Angewandte Chemie·Euan R KayFrancesco Zerbetto
Jul 26, 2008·Nature Nanotechnology·Jonathan Bath, Andrew J Turberfield
Mar 20, 2008·Small·Nicolas H VoelckerM Reza Ghadiri
Jun 18, 2009·Chemical Communications : Chem Comm·Huajie Liu, Dongsheng Liu
Apr 21, 2009·Angewandte Chemie·Johann ElbazItamar Willner
Nov 30, 2005·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Igor M KulićHelmut Schiessel
Feb 18, 2006·Angewandte Chemie·Chandrasekhar V Miduturu, Scott K Silverman
Feb 14, 2006·Angewandte Chemie·Udo Feldkamp, Christof M Niemeyer
Apr 3, 2019·Advanced Healthcare Materials·Shaoli LiuBaoquan Ding
Feb 21, 2006·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Matthew T DowntonHeiner Linke
Jun 6, 2019·Annual Review of Biomedical Engineering·Dominic Scalise, Rebecca Schulman
Dec 19, 2013·Lab on a Chip·Vincent ChanRashid Bashir
Jul 17, 2013·Macromolecular Rapid Communications·Xiangling XiongWeihong Tan
Jun 28, 2017·Proceedings of the National Academy of Sciences of the United States of America·Chikako KurokawaMiho Yanagisawa
Dec 31, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yufang WangN P Ong
Jan 22, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Markus PortoJoseph Klafter
May 18, 2007·The Journal of Physical Chemistry. B·Wenli DengAlexander D Q Li
Sep 24, 2005·Nano Letters·Hari ShroffJan Liphardt
Oct 23, 2008·Nano Letters·Sudheer SahuJohn H Reif
Dec 29, 2006·Small·Friedrich C Simmel, Wendy U Dittmer
May 9, 2012·Nano Letters·Fei ZhangHao Yan
Feb 22, 2013·ACS Applied Materials & Interfaces·Ronit FreemanItamar Willner
Jul 25, 2013·Journal of the American Chemical Society·Toma E TomovEyal Nir
Feb 5, 2019·Chemical Reviews·Friedrich C SimmelHari R Singh
Aug 31, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Preston B LandonRatnesh Lal

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