Using Dog Scent Detection as a Point-of-Care Tool to Identify Toxigenic Clostridium difficile in Stool

Open Forum Infectious Diseases
Maureen T TaylorJeff Powis

Abstract

We evaluated the operating characteristics of 2 comparably trained dogs as a "point-of-care" diagnostic tool to detect toxin gene-positive Clostridium difficile. Although each dog could detect toxin gene-positive C difficile in stool specimens with sensitivities of 77.6 and 92.6 and specificities of 85.1 and 84.5, respectively, interrater reliability is only modest (Cohen's kappa 0.52), limiting widespread application.

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Citations

Oct 23, 2019·International Journal of Environmental Research and Public Health·Aubrey H FineZenithson Ng
Jul 25, 2020·BMC Infectious Diseases·Paula JendrnyHolger Andreas Volk
May 30, 2020·Sleep & Breathing = Schlaf & Atmung·Jenni VaarnoAnni Koskinen
Nov 18, 2019·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E Cambau, M Poljak
Jun 22, 2021·Journal of Medical Virology·Silvia AngelettiMassimo Ciccozzi
Jul 29, 2021·BMC Infectious Diseases·Paula JendrnyHolger Andreas Volk
Apr 13, 2019·Infection Prevention in Practice·M K CharlesE Bryce
Aug 21, 2021·BMC Infectious Diseases·Paula JendrnyHolger Andreas Volk
Jun 9, 2021·Disaster Medicine and Public Health Preparedness·Cynthia M OttoLois Privor-Dumm

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