Using Electronic Health Records to Identify Adverse Drug Events in Ambulatory Care: A Systematic Review

Applied Clinical Informatics
Chenchen FengAllison B McCoy

Abstract

We identified the methods used and determined the roles of electronic health records (EHRs) in detecting and assessing adverse drug events (ADEs) in the ambulatory setting. We performed a systematic literature review by searching PubMed and Google Scholar for studies on ADEs detected in the ambulatory setting involving any EHR use published before June 2017. We extracted study characteristics from included studies related to ADE detection methods for analysis. We identified 30 studies that evaluated ADEs in an ambulatory setting with an EHR. In 27 studies, EHRs were used only as the data source for ADE identification. In two studies, the EHR was used as both a data source and to deliver decision support to providers during order entry. In one study, the EHR was a source of data and generated patient safety reports that researchers used in the process of identifying ADEs. Methods of identification included manual chart review by trained nurses, pharmacists, and/or physicians; prescription review; computer monitors; electronic triggers; International Classification of Diseases codes; natural language processing of clinical notes; and patient phone calls and surveys. Seven studies provided examples of search phrases, laboratory va...Continue Reading

Citations

May 6, 2021·BMC Medical Informatics and Decision Making·Pilar López-ÚbedaStefan Schulz
Jun 24, 2021·Applied Clinical Informatics·Diana J Schreier, Jenna K Lovely
Sep 7, 2021·Health Services Research·Rocco FriebelLaia Maynou

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