Abstract
This study seeks to determine whether the use of Eulerian video magnification (EVM) increases the detection of muscle fasciculations in people with amyotrophic lateral sclerosis (PALS) compared with direct clinical observation (DCO). Thirty-second-long video recordings were taken of 9 body regions of 7 PALS and 7 controls, and fasciculations were counted by DCO during the same 30-s period. The video recordings were then motion magnified and reviewed by 2 independent assessors. In PALS, median fasciculation count per body region was 1 by DCO (range 0-10) and 3 in the EVM recordings (range 0-15; P < 0.0001). EVM revealed more fasciculations than DCO in 61% of recordings. In controls, median fasciculation count was 0 for both DCO and EVM. Compared with DCO, EVM significantly increased the detection of fasciculations in body regions of PALS. When it is used to supplement clinical examination, EVM has the potential to facilitate the diagnosis of ALS. Muscle Nerve 56: 1063-1067, 2017.
References
Dec 1, 1991·Muscle & Nerve·M Behnia, J J Kelly
Jan 1, 1980·Physiological Reviews·F Buchthal, H Schmalbruch
Aug 1, 1996·Journal of Neurology·C D ReimersC Kurth
Jul 24, 2001·Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases·B R BrooksUNKNOWN World Federation of Neurology Research Group on Motor Neuron Diseases
May 8, 2002·Muscle & Nerve·Jun LiMark Bromberg
Jul 23, 2005·Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases·C PaillisseV Meininger
Jun 19, 2007·Lancet·J D Mitchell, G D Borasio
Jan 1, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Mamede de CarvalhoMichael Swash
Jun 18, 2009·Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases·Jiske FermontMachiel J Zwarts
Jun 12, 2010·Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases·Werner A BoekesteinMachiel J Zwarts
Jan 17, 2012·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ilse M P ArtsH Jurgen Schelhaas
Dec 3, 2013·Rinshō shinkeigaku = Clinical neurology·Sonoko Misawa
Mar 1, 2014·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Malgorzata GawelAnna Kamińska
Sep 11, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A GrimmJ Grosskreutz
Dec 9, 2014·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Federica AgostaUNKNOWN WFN Research Group on ALS/MND
Feb 13, 2015·Rinshō shinkeigaku = Clinical neurology·Masahiro Sonoo, Mana Higashihara
Feb 13, 2015·Rinshō shinkeigaku = Clinical neurology·Kota Bokuda, Toshio Shimizu
Nov 23, 2016·IEEE Transactions on Pattern Analysis and Machine Intelligence·Abe DavisWilliam T Freeman
Citations
Aug 29, 2019·Primates; Journal of Primatology·Emilie MelvinCharles L Nunn
Sep 23, 2018·Journal of Neurology·Stefan WilliamsChristopher D Graham
Dec 14, 2019·BMC Biology·Henrik LauridsenJonathan T Butcher
Nov 24, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Stefan WilliamsJane E Alty