Using Extended-Release Injectable Aripiprazole for the Successful Treatment of Depressive Symptoms in Bipolar I Disorder

Case Reports in Psychiatry
Joseph Kuo, Shih-Ku Lin

Abstract

Extended-release injectable (ERI) aripiprazole is indicated for schizophrenia and maintenance monotherapy of bipolar I disorder. Clinical trials of aripiprazole failed to exhibit efficacy in the treatment of bipolar depression. It has been suggested that relatively high doses, rapid titration of dose, a high dropout rate, and a high placebo effect might be the reasons of its ineffectiveness. Here, we report a case of a 39-year-old woman with bipolar depression who was successfully treated with ERI aripiprazole.

References

Jan 19, 2007·Journal of Affective Disorders·Susan L McElroyPaul E Keck
Jan 22, 2008·Journal of Clinical Psychopharmacology·Michael E ThaseRandall Owen
Feb 15, 2008·Journal of Affective Disorders·Robert T DunnS Nassir Ghaemi
Dec 16, 2016·Journal of Clinical Psychopharmacology·Tammas Kelly, Daniel Z Lieberman

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