PMID: 16617947Apr 19, 2006Paper

Using Failure Mode and Effects Analysis for safe administration of chemotherapy to hospitalized children with cancer

Joint Commission Journal on Quality and Patient Safety
Deborah L RobinsonJeanenne Clark

Abstract

The administration of chemotherapy to hospitalized children with cancer is a complex and high-risk process. A team divided the process into three areas--prescribing, dispensing, and administration--and used Failure Mode and Effects Analysis (FMEA) to identify the elements of risk and implement appropriate strategies. For each area, potential failures within subprocesses were assigned risk priority numbers (RPNs), reflecting their frequency, severity, and detectability. The team made prescribing and administration, the areas with the highest RPNs, the focus of most of its strategies, which were introduced and completed in 2002. The potential prescribing error rate decreased from 23% to 14%; use of preprinted standard order sets increased from 22% to 45% in 2003 (one year after the FMEA was conducted) and 76% in 2005. Actual dispensing errors decreased from 3 to 1, and the actual administration errors from 4 to 3. Computerized order entry systems would only affect prescribing, dispensing, and administering, which would still be done manually, resulting in potential for failure. The FMEA project will be an ongoing part of providing safe chemotherapy treatments.

References

Sep 25, 2001·Archives of Pediatrics & Adolescent Medicine·R KaushalD W Bates
May 28, 2004·Archives of Pathology & Laboratory Medicine·Jan S Krouwer
Apr 27, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Wayne Adachi, Amy E Lodolce

❮ Previous
Next ❯

Citations

May 2, 2012·Journal of Oncology Practice·Saul N WeingartMichael J Hassett
Aug 21, 2020·Translational Vision Science & Technology·Yuchen XieDaniel S W Ting
Aug 28, 2020·Postgraduate Medical Journal·Jayaweera A Lakshika AnjaleeNithushi R Samaranayake
Sep 18, 2009·Medical Care Research and Review : MCRR·Michel DückersMichel Wensing
Apr 14, 2011·Journal of the American Medical Informatics Association : JAMIA·Adam G DunnWayne Wobcke
Sep 21, 2013·Journal of Nursing Care Quality·Beilei Belinda ZhangTimothy I Morgenthaler
Mar 1, 2012·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Diane S DennyDigant Gupta
Dec 19, 2019·Journal of Evaluation in Clinical Practice·Hu-Chen LiuLiang Wang
Nov 19, 2009·Journal of Patient Safety·Nada Atef SheblNick Barber
Feb 28, 2008·Nursing Management·Martha A RiehleKristiina Hyrkäs
May 3, 2011·Journal of Oncology Practice·Saul N WeingartMaureen Connor
Jul 14, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Peter C WierengaSusanne M Smorenburg
May 5, 2016·Journal of Clinical Pharmacy and Therapeutics·D F Bannan, M P Tully
Apr 26, 2008·Journal of the American Medical Informatics Association : JAMIA·Pascal BonnabryChristian Lovis
Nov 19, 2010·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Christine M Collins, Khaled A Elsaid
Jun 29, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jose Javier Arenas VillafrancaVicente Faus Felipe
Aug 26, 2021·Revista brasileira de enfermagem·Luciana Andrade de LimaRodrigo Assis Neves Dantas
Dec 3, 2008·Pediatrics·George R KimUNKNOWN Council on Clinical Information Technology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Wayne Adachi, Amy E Lodolce
Drug Safety : an International Journal of Medical Toxicology and Drug Experience
Desireé L Kunac, David M Reith
© 2022 Meta ULC. All rights reserved