PMID: 9880278Jan 8, 1999Paper

Using fetal nuchal translucency to screen for major congenital cardiac defects at 10-14 weeks of gestation: population based cohort study

BMJ : British Medical Journal
J A HyettKypros H Nicolaides

Abstract

To examine the utility of measuring fetal nuchal translucency thickness in screening for major defects of the heart and great arteries at 10-14 weeks of gestation. Population based cohort study. 29 154 singleton pregnancies with chromosomally normal fetuses at 10-14 weeks of gestation. Fetal medicine centre in London. Prevalence of major defects of the heart and great arteries. Of 50 cases with major defects of the heart and great arteries (prevalence 1.7 per 1000 pregnancies) 28 (56%, 95% confidence interval 42% to 70%) were in the subgroup of 1822 pregnancies with fetal nuchal translucency thicknesses above the 95th centile of the normal range. The positive and negative predictive values for this cut off point of nuchal translucency thickness were 1.5% and 99.9% respectively. Measurement of fetal nuchal translucency thickness-traditionally used to identify fetuses at high risk of aneuploidy-at 10-14 weeks of gestation can identify a large proportion of fetuses with major defects of the heart and great arteries.

References

Sep 1, 1991·American Journal of Obstetrics and Gynecology·L A Dolkart, F T Reimers
Sep 1, 1987·American Journal of Obstetrics and Gynecology·J A CopelC S Kleinman
Mar 1, 1971·Circulation·S C MitchellH W Berendes
Nov 1, 1984·British Heart Journal·L D AllanM J Tynan
Jun 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E TegnanderD T Linker
May 1, 1995·Pediatric Cardiology·J I Hoffman
Nov 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M A RusticoG Mandruzzato
Dec 1, 1995·British Journal of Obstetrics and Gynaecology·P P PandyaK H Nicolaides
Mar 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R J SnijdersK H Nicolaides
Apr 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J HyettK H Nicolaides
Jul 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M Meyer-WittkopfG K Sharland
Mar 17, 1997·American Journal of Medical Genetics·J HyettK Nicolaides
Dec 31, 1997·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J A HyettK H Nicolaides
Dec 4, 1997·The New England Journal of Medicine·P TaipaleP Ylöstalo
Apr 18, 1998·Lancet·J S CarvalhoY Ville

❮ Previous
Next ❯

Citations

Mar 16, 2007·Pediatric Surgery International·Kokila Lakhoo
Mar 3, 2007·Archives of Gynecology and Obstetrics·Peter SchmidtAlexander Scharf
Jan 28, 2009·World Journal of Pediatrics : WJP·Mathias NelleMatthias Meyer-Wittkopf
Sep 3, 2002·Clinica Chimica Acta; International Journal of Clinical Chemistry·Peter A Benn
Oct 18, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C TennstedtM Dietel
Feb 23, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Hajnalka OrvosJános Szabó
Aug 10, 2000·Journal of the American College of Cardiology·I C HuggonG K Sharland
Sep 25, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Eleni MavridesBaskaran Thilaganathan
Jan 10, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G D MichailidisD L Economides
Mar 6, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·S F WongH D McIntyre
Feb 15, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T GhiK H Nicolaides
Feb 15, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E ZohavS Segal
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·H J JouF J Hsieh
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G D Michailidis, D L Economides
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E MavridesJ S Carvalho
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C M Bilardo
May 8, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C M BilardoK Hecher
May 8, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R Chaoui
Aug 8, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A HiippalaV Hiilesmaa
Aug 8, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y Ville
May 2, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A MachlittR Chaoui
Jul 9, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M C HaakJ M G Van Vugt
Jun 12, 2009·The New England Journal of Medicine·Deborah A Driscoll, Susan Gross
Apr 24, 2001·Current Opinion in Obstetrics & Gynecology·C M BilardoE Pajkrt
Aug 24, 1999·British Journal of Obstetrics and Gynaecology·N ZosmerK H Nicolaides
Jan 15, 2009·Epilepsia·Umberto AgugliaAlberto Verrotti
Jan 8, 1999·BMJ : British Medical Journal·B W Mol
Jan 12, 2002·BMJ : British Medical Journal·Josephine Venn-Treloar
Mar 27, 2001·Journal of Clinical Pathology·T M Reynolds
Jan 1, 2009·Annals of Pediatric Cardiology·John M Simpson
Jan 20, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Katherine W FongJo-Ann Johnson
Dec 18, 2013·Best Practice & Research. Clinical Obstetrics & Gynaecology·Merel BakkerCaterina M Bilardo
Jun 12, 2013·Seminars in Fetal & Neonatal Medicine·Asma Khalil, Kypros H Nicolaides
Aug 2, 2005·Obstetrics and Gynecology·Fergal D MaloneUNKNOWN FASTER Trial Research Consortium
Jan 6, 2006·Obstetrics and Gynecology·Karl Oliver KaganKypros H Nicolaides
Apr 4, 2006·Obstetrics and Gynecology·Peter O'LearyRosanne Stock
Feb 3, 2007·Obstetrics and Gynecology·Lynn L SimpsonMary E D'Alton
May 25, 2011·Obstetrics and Gynecology·Susana PereiraKypros H Nicolaides
Mar 4, 2000·Heart·L Allan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
J A HyettK H Nicolaides
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
E MavridesJ S Carvalho
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
G D Michailidis, D L Economides
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
J A HyettK H Nicolaides
© 2021 Meta ULC. All rights reserved