Using genetic admixture to study the biology of obesity traits and to map genes in admixed populations

Nutrition Reviews
José R Fernandez, Mark D Shiver

Abstract

Differences among ethnic and racial groups in obesity-related traits have been clearly established in the scientific literature. To explore the genetic component underlying these differences, the genetic admixture approach has been used. In this approach, ancestry informative genetic markers are used to estimate a quantitative value representing the degree of ancestral background in individuals of admixed genetic background. Genetic admixture has been successfully used to explain racial and ethnic variation in obesity related traits; however, the understanding and measure of cultural and environmental components that also influence these phenotypes still requires further exploration.

References

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Citations

Sep 30, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M CardelJ R Fernández
Mar 18, 2016·Genetica·Bruna Ribeiro de Andrade RamosMárcia Guimarães da Silva
Mar 20, 2015·The British Journal of Sociology·Troy Duster
Jun 22, 2006·American Journal of Human Biology : the Official Journal of the Human Biology Council·Jane L P RoyBradley R Newcomer
May 8, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Diego Costa AsturMoises Cohen
Feb 19, 2017·BMC Medical Genetics·Maria Paula Barbieri D'EliaHélio Amante Miot
Mar 19, 2021·Clinical and Experimental Pharmacology & Physiology·Zunera ChauhdaryMuhammad Sajid Hamid Akash

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