Abstract
Results of a study to apply lean methodology to an inpatient pharmacy workflow to optimize timely administration of Centers for Medicare and Medicaid Services (CMS)-approved antibiotics for patients with severe sepsis or septic shock are presented. This quasi-experimental study was conducted at an 802-bed institution using lean methodology to assess the inpatient pharmacy workflow for dispensing antibiotics to adult patients. The preintervention and postintervention phases occurred from February to September, 2015, and from October 2015 to May 2016, respectively. Patients were included if they were hospitalized with an intensive care department 9 or 10 code for severe sepsis or septic shock, had an order for a CMS-approved antibiotic, and met clinical criteria for severe sepsis or septic shock. Patients were excluded if they received first-dose antibiotics in the emergency department. The primary outcome was time from CMS-approved antibiotic order entry to medication administration. Secondary outcomes included timeliness of individual workflow dispensing parameters, patient outcomes, and compliance with the newly implemented workflow. A total of 102 patients were included, 54 in the preintervention and 48 in the postinterventio...Continue Reading
References
Apr 21, 2006·Critical Care Medicine·Anand KumarMary Cheang
Dec 14, 2006·JAMA : the Journal of the American Medical Association·Rachel M Werner, Eric T Bradlow
Nov 6, 2009·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Barbara L HintzenBrian S Milavitz
Mar 1, 2011·The American Journal of Emergency Medicine·Emilie S PowellJoe Feinglass
Oct 4, 2011·Critical Care Medicine·Tara LaguPeter K Lindenauer
Feb 4, 2012·Shock·Kyeongman JeonIk Joon Jo
Jan 29, 2013·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
Jan 31, 2013·Intensive Care Medicine·R P DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup
Feb 28, 2013·Critical Care Medicine·David F GaieskiBrendan G Carr
May 4, 2013·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jennifer HlubockyJohn S Clark
Jun 12, 2013·Joint Commission Journal on Quality and Patient Safety·Joan M ChingC Craig Blackmore
Nov 10, 2013·Critical Care Medicine·Elizabeth K StevensonAllan J Walkey
Apr 11, 2014·Critical Care Medicine·Ricard FerrerMitchell M Levy
Aug 26, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Peter SullivanEric D Cabie
Jan 18, 2015·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·C Brett BenfieldMichael Heung
Mar 10, 2015·Critical Care Medicine·Andrew J GoodwinDee W Ford
Aug 25, 2015·American Heart Journal·Bimal R ShahEric D Peterson
Citations
May 8, 2020·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Tyler A VestStephen F Eckel
Dec 24, 2019·The Annals of Pharmacotherapy·Andrew J CrannageTricia M Berry
Aug 8, 2020·International Journal of Environmental Research and Public Health·Carlos Zepeda-LugoGuilherme Tortorella